Which term means a state of exhaustion or a loss of strength or endurance?

Question

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Fatigue is the term that specifically refers to a state of exhaustion or a loss of strength or endurance. Lethargic and malaise both involve a feeling of general weakness or discomfort, but they may not necessarily be due to physical exertion or overexertion. Pandemic is a term that refers to a widespread disease or epidemic affecting many countries or regions.

Which Term Means a State of Exhaustion or a Loss