A mutation causing an amino acid change in an enzyme that affects the turnover number kcat will always affect the KM as well.

Name: A mutation causing an amino acid change in an enzyme that affects the turnover number kcat will always affect the KM as well.
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Question

Quizplus · Accepted Answer

A mutation causing an amino acid change in an enzyme that affects the turnover number kcat may or may not affect the KM. These two parameters are independent and can be affected differently by different mutations.

A Mutation Causing an Amino Acid Change in an Enzyme