Four-year old Jacob has demonstrated a significant loss of previously acquired skills,following an apparently normal development.Jacob would be most likely to be diagnosed with:

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Childhood disintegrative disorder, also known as Heller's syndrome, is a rare condition in which children between the ages of 2 and 10 years old experience a marked regression in multiple areas of functioning after a period of typical development. This can include the loss of previously acquired skills, such as social interactions, communication, and intellectual functioning. Autism, Asperger's disorder, and Rett's disorder may also involve developmental delays and impairments in social functioning, but they do not typically involve such a significant loss of previously acquired skills.

Four-Year Old Jacob Has Demonstrated a Significant Loss of Previously