The pre-B-cell receptor provides an important signal that induces transition of pro-B cells to pre-B cells. An important characteristic of this receptor is that:
A) It signals without binding to an extracellular ligand.
B) It is composed of immunoglobulin heavy chains and the VJ region of a rearranged $\lambda$ light chain.
C) It is expressed at very high levels on the surface of the pro-B cell.
D) It signals without requiring association with B-cell receptor signaling subunits, Ig$\alpha$ and Ig$\beta$.
E) It signals without requiring the B-cell receptor signaling kinase, BTK.

Question

Quizplus · Accepted Answer

The pre-B-cell receptor signals without binding to an extracellular ligand, which is a unique characteristic distinguishing it from other receptors that typically require ligand binding to initiate signaling.

The Pre-B-Cell Receptor Provides an Important Signal That Induces Transition λ\lambdaλ

The Pre-B-Cell Receptor Provides an Important Signal That Induces Transition $\lambda$