IgM is the first antibody isotype secreted following activation of a naive B cell. IgM is found at high concentrations in the serum, and is found as a very high molecular weight complex. This high molecular weight complex is composed of:
A) A single IgM monomer plus monomers of IgA and IgG
B) A single IgM monomer bound to several non-immunoglobulin serum proteins
C) A single IgM monomer bound to serum complement components
D) A pentamer of IgM monomers
E) Two dimers of IgM plus IgD forming a tetrameric complex
Correct Answer:
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