Secondary (or peripheral) lymphoid organs are sites for initiation of adaptive immune responses. Given the rarity of lymphocytes specific for any given antigen and the vast amount of body tissue that must be protected, the system of secondary lymphoid tissues is efficient because:
A) It concentrates antigens in centralized locations for rare lymphocytes to encounter
B) It provides the optimal environment for the rapid proliferation of lymphocytes
C) It traps the pathogens and antigens in a contained environment so they cannot spread to other tissues in the body
D) It helps the innate immune cells eliminate the infection by using lymphatic fluid to drain pathogens from the infected tissue
E) It filters the lymph fluid and removes pathogenic organisms before they can enter the bloodstream
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