A patient is receiving chemotherapy for the treatment of leukemia.While providing care for this patient,which clinical manifestations would indicate tumor lysis syndrome?

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Quizplus · Accepted Answer

Tumor lysis syndrome is a potential complication of chemotherapy, particularly in patients with rapidly growing tumors such as leukemia. It results from the rapid destruction of cancer cells, which leads to the release of intracellular contents such as potassium, phosphate, and uric acid. As a result, electrolyte imbalances and metabolic abnormalities such as hyperkalemia, hyperphosphatemia, and hyperuricemia can occur. These metabolic disturbances can lead to multiple organ dysfunction, including central nervous system dysfunction, which can manifest as altered levels of consciousness. Thrombocytopenia, respiratory distress, and upper-extremity edema are not specific clinical manifestations of tumor lysis syndrome. Thrombocytopenia may be a side effect of chemotherapy, but it is not directly related to tumor lysis syndrome. Respiratory distress could occur if the cancer is affecting the lungs, but it is not specific to tumor lysis syndrome. Upper-extremity edema could be a sign of a blood clot or lymphedema, but it is not typically associated with tumor lysis syndrome.

A Patient Is Receiving Chemotherapy for the Treatment of Leukemia