The high fidelity of DNA replication is due primarily to immediate error correction by the 3' $\rightarrow$5' exonuclease (proofreading) activity of the DNA polymerase. Some incorrectly paired bases escape this proofreading, and further errors can arise from challenges to the chemical integrity of the DNA. List the four classes of repair mechanisms that the cell can use to help correct such errors.

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The Answer of The high fidelity of DNA replication is due primarily to immediate error correction by the 3' $\rightarrow$5' exonuclease (proofreading) activity of the DNA polymerase. Some incorrectly paired bases escape this proofreading, and further errors can arise from challenges to the chemical integrity of the DNA. List the four classes of repair mechanisms that the cell can use to help correct such errors.

The High Fidelity of DNA Replication Is Due Primarily to Immediate