Although glycolysis produces four molecules of ATP by substrate-level phosphorylation, the net gain of ATP for the cell is two molecules. This is due to the fact that glycolysis is-at first-endergonic.

Question

Quizplus · Accepted Answer

Glycolysis consumes 2 ATP molecules in its early steps to activate glucose, resulting in a net gain of 2 ATP molecules by the end of the process, despite 4 ATP molecules being produced in later steps.

Although Glycolysis Produces Four Molecules of ATP by Substrate-Level Phosphorylation