Which regulatory mechanism is important in keeping glycolysis and the citric acid cycle in relative balance to each other?

Question

Quizplus · Accepted Answer

Citrate is an intermediate of the citric acid cycle and acts as an allosteric inhibitor of phosphofructokinase-1 (PFK-1), a key regulatory enzyme in glycolysis. This inhibition helps to balance the flow of carbon through glycolysis and the citric acid cycle, preventing excessive accumulation of citrate and ensuring efficient energy production.

Which Regulatory Mechanism Is Important in Keeping Glycolysis and the Citric