G Protein-Coupled Receptors Are Transmembrane Receptors Involved in Cell Signaling

G protein-coupled receptors are transmembrane receptors involved in cell signaling. The amino acid sequence of these proteins reveals that the polypeptide chain of the protein has seven hydrophobic regions. Based on this information, what can you conclude about how the protein is associated with the cell membrane?

A) The receptor is likely to be a peripheral membrane protein.
B) The polypeptide chain is likely to span the membrane once.
C) The polypeptide chain is likely to span the membrane seven times.
D) The polypeptide chain is likely to span the membrane fourteen times.
E) The receptor is likely to be synthesized on free ribosomes.