What is the major end product of the following reaction series?

Question

Quizplus · Accepted Answer

The reaction series is referring to the metabolic pathway of the breakdown of branched-chain amino acids (BCAAs) - valine, leucine, and isoleucine. The major end product of this pathway is acetyl-CoA, which can be used in the citric acid cycle or in fatty acid synthesis. The answer choices are all BCAAs, but none of them are the major end product. Valine, leucine, and isoleucine are converted into their respective alpha-keto acids by transamination, which are then further metabolized into acetyl-CoA via the branched-chain alpha-keto acid dehydrogenase complex. Therefore, the best choice is E) Val, which is one of the three amino acids involved in this pathway.

What Is the Major End Product of the Following Reaction