Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino

تمرين 2

A middle-aged woman taking the breast cancer drug Tamoxifen for ten years became concerned when she saw a news report with disturbing information. In some women, the drug made their cancer more aggressive and more likely to spread. Other women with breast cancer, the report stated, do not respond to Tamoxifen at all, and 30 to 40 percent of women who take the drug eventually become resistant to chemotherapy. The woman contacted her oncologist to ask some questions:
Why do most cancers eventually become resistant to a specific chemotherapeutic drug?