Genetics: Analysis and Principles 5th Edition by Robert Brooker

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Within a protein, certain amino acids are positively charged (e.g., lysine and arginine), some are negatively charged (e.g., glutamate and aspartate), some are polar but uncharged, and some are non-polar. If you knew that a DNA-binding protein was recognizing the DNA backbone rather than base sequences, which amino acids in the protein would be good candidates for interacting with the DNA