Genetics: Analysis and Principles 5th Edition by Robert Brooker

تمرين 26

Trinucleotide repeat expansions (TNREs) are associated with several different human inherited diseases. Certain types of TNREs produce a long stretch of glutamines (an amino acid) within the encoded protein. This long stretch of glutamines somehow inhibits the function of the protein, thereby causing a disorder. When a TNRE exerts its detrimental effect by producing a glutamine stretch, are the following statements true or false
a. The TNRE is within the coding sequence of the gene
b. The TNRE prevents RNA polymerase from transcribing the gene properly
c. The trinucleotide sequence is CAG
d. The trinucleotide sequence is CCG.