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Molecular Biology 5th Edition by Robert Weaver
النسخة 5الرقم المعياري الدولي: 978-0073525327Molecular Biology 5th Edition by Robert Weaver
النسخة 5الرقم المعياري الدولي: 978-0073525327 تمرين 4
Consider the process of bringing a new aminoacyl-tRNA to the A site, as revealed by x-ray crystallography. Describe the probable effects of each of the following mutations on speed and fidelity of translation:
a. A mutation in the 16S rRNA that facilitates "domain closure" in the 30S subunit.
b. A mutation in the acceptor stem of the tRNA that inhibits the change in conformation that normally helps the tRNA bend into the A/T state.
c. A mutation in switch I of EF-Tu that strengthens its binding to the acceptor stem of tRNA.
d. Mutating His 84 of EF-Tu to Alanine.
a. A mutation in the 16S rRNA that facilitates "domain closure" in the 30S subunit.
b. A mutation in the acceptor stem of the tRNA that inhibits the change in conformation that normally helps the tRNA bend into the A/T state.
c. A mutation in switch I of EF-Tu that strengthens its binding to the acceptor stem of tRNA.
d. Mutating His 84 of EF-Tu to Alanine.
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موثّق
Translation is the process of producing ...
Molecular Biology 5th Edition by Robert Weaver
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