Math and Dosage Calculations for Health Care 3rd Edition by James Whaley, Kathryn Booth, Booth Kathryn

تمرين 40

The patient: 71-year-old male, 5? 10? tall, 193 lb, CL CR of 50 mL/min.
Ordered: Capastat 600 mg IM qd
On hand: Capastat sulfate, diluted to 350 mg/mL
According to the package insert, the estimated daily dosage required to maintain a steady level of drug is 1.29 mg/kg for creatinine clearance of 0 mL/min; 2.43 mg/kg for 10 mL/min; 3.58 mg/kg for 20 mL/min; 4.72 mg/kg for 30 mL/min; 5.87 mg/kg for 40 mL/min; 7.01 mg/kg for 50 mL/min; and 8.16 mg/kg for 60 mL/min.