Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams

تمرين 34

Which statement best explains current theory on the etiology of aplastic anemia? (Objective 3)
A) An immune mechanism, possibly involving abnormal T lymphocytes, leads to suppression of hematopoietic stem cells.
B) A deficiency of cytokines, such as erythropoietin, results in hematopoietic stem cells which are incapable of mitosis.
C) Hematopoietic stem cells are crowded out by neoplastic cells invading the bone marrow.
D) The bone marrow microenvironment is damaged and rendered nonsupportive of the growth of hematopoietic stem cells.