Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams

تمرين 31

Mai, a 35-year-old woman, saw her physician. She complained of weakness, low-grade fever, periods of forgetfulness, and memory loss for the last week or so. She denied any viral illness before the onset of symptoms. She was on oral contraceptives but was not taking any other drugs. Her initial laboratory tests showed:
Consider reflex testing that could be helpful in identifying the cause of the anemia.
Mai's peripheral blood smear showed moderate schistocytes and polychromasia.
As Mai was questioned further, she indicated that she had noticed a large number of bruises on her extremities. Her platelet count was 31 * 109/L. She had a 2.5% reticulocyte count.
Mai's PT and APTT were slightly prolonged. The fibrinogen levels were slightly decreased.
What do these findings indicate about the underlying problem?
Mai's symptoms continued to become worse with frequent seizures, headaches, and dizziness. Her urinalysis results showed a 2+ protein and moderate blood. However, she had normal urinary volume.
Based on these results, what is the most likely condition associated with these clinical and laboratory results? Explain.