Biology 3rd Edition by Peter Russell, Paul Hertz, Beverly McMillan

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The shapes of a protein's domains often give clues to its functions.For example, protein HLA (human leukocyte antigen) is a type of recognition protein on the outer surface of all vertebrate body cells.Certain cells of the immune system use HLAs to distinguish self (the body's own cells) from nonself (invading cells)Each HLA protein has a jawlike region that can bind to molecular parts of an invader.It thus alerts the immune system that the body has been invaded.Speculate on what might happen if a mutation makes the jawlike region misfold.