Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni

تمرين 9

Inhibitors: Wrong Again. For each of the following false statements, change the statement to make it true and explain your reasoning.
(a)Diisopropyl fluorophosphate binds covalently to the hydroxyl group of a specific amino acid residue of the target enzyme and is therefore almost certainly an allosteric effector.
(b)The enzyme hexokinase is inhibited by its own product, glucose-6-phosphate, and is therefore an example of feedback inhibition.
(c)Glycogen synthase, like glycogen phosphorylase, is active in the phosphorylated form and inactive in the dephosphory- lated form.
(d)An enzyme that is subject to allosteric activation is most likely to catalyze the final reaction in a biosynthetic pathway.
(e)If researchers claim that an enzyme is allosterically activated by compound A and allosterically inhibited by compound B, one of these claims must be wrong.