Biology 8th Edition by Kenneth Mason ,Jonathan Losos,Susan Singer,Peter Raven,George Johnson

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How can a point mutation lead to a nonsense mutation
A) Changing a single base has no effect on the protein.
B) Changing a single base leads to a premature termination of translation.
C) Changing a single base within a codon from an A to a C.
D) The addition or deletion of a base alters the reading frame for the gene.