Essential Genetics 6th Edition by Daniel Hartl

تمرين 8

The accompanying gel diagram shows the pattern of bands observed in a Southern blot for three linked RFLPs in and flanking the p53 gene in a family in which Li-Fraumeni syndrome is found. Shown are an affected mother, an unaffected father, and one affected son. The bands AL and AS are for one RFLP (with alleles AL and AS ), and the bands BL and BS are for another RFLP (with alleles BL and BS ). The
in the son. If DNA from tumor cells in the son were assayed for these RFLPs, what pattern of bands would be expected from each of the following cells?