
Essentials of Genetics 9th Edition by Michael Palladino William Klug, Michael Cummings, Charlotte Spencer
النسخة 9الرقم المعياري الدولي: 978-1292108865
Essentials of Genetics 9th Edition by Michael Palladino William Klug, Michael Cummings, Charlotte Spencer
النسخة 9الرقم المعياري الدولي: 978-1292108865 تمرين 1
At loose ends
A researcher was asked if his work on human telomere replication was related to any genetic disorders. He replied that one might think that any such mutation would be lethal during early development, but in fact a rare human genetic disorder affecting telomeres is known. This disorder, dyskeratosis congenita (DKC), is associated with mutations in the protein subunits of telomerase, the enzyme responsible for replicating the ends of eukaryotic chromosomes. Initial symptoms appear in tissues derived from rapidly dividing cells, including the skin, nails, and bone marrow, and first affect children between the ages of 5 and 15 years.
This disorder raises several interesting questions.
How could such individuals survive?
A researcher was asked if his work on human telomere replication was related to any genetic disorders. He replied that one might think that any such mutation would be lethal during early development, but in fact a rare human genetic disorder affecting telomeres is known. This disorder, dyskeratosis congenita (DKC), is associated with mutations in the protein subunits of telomerase, the enzyme responsible for replicating the ends of eukaryotic chromosomes. Initial symptoms appear in tissues derived from rapidly dividing cells, including the skin, nails, and bone marrow, and first affect children between the ages of 5 and 15 years.
This disorder raises several interesting questions.
How could such individuals survive?
التوضيح
Dyskeratosis congentia (DKC) is mostly o...
Essentials of Genetics 9th Edition by Michael Palladino William Klug, Michael Cummings, Charlotte Spencer
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