Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann

تمرين 9

Exposure of DNA to the chemotherapy drug, cisplat-in, causes the formation of intrastrand cross-links between two adjacent guanines in DNA. Explain why the instrastrand crosslink between two adjacent guanines is a better candidate for nucleotide excision repair rather than for base excision repair.