Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann

تمرين 1

If the 5? splice site sequence changed from 5?-GUAAGU-3? to 5?-GUAUGU-3?, predict the effect of the sequence change on U1 binding and U6 snRNP binding in an in vitro protein-RNA binding assay.