
Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
النسخة 6الرقم المعياري الدولي: 978-0815345244
Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
النسخة 6الرقم المعياري الدولي: 978-0815345244 تمرين 9
Which statements are true? explain why or why not.
-0 Generation of induced pluripotent stem (iPS) cells was first accomplished using retroviral vectors to carry the OSKM
set of tran- scription regulators into cells. The efficiency of fibroblast reprogramming was typically low (0.01%), in part because large numbers of retroviruses must integrate to bring about reprogramming and each integration event carries with it the risk of inappropriately disrupting or activating a critical gene. In what other ways, or other forms, do you suppose you might deliver the OSKM transcription regula- tors so as to avoid these problems? 
-0 Generation of induced pluripotent stem (iPS) cells was first accomplished using retroviral vectors to carry the OSKM
set of tran- scription regulators into cells. The efficiency of fibroblast reprogramming was typically low (0.01%), in part because large numbers of retroviruses must integrate to bring about reprogramming and each integration event carries with it the risk of inappropriately disrupting or activating a critical gene. In what other ways, or other forms, do you suppose you might deliver the OSKM transcription regula- tors so as to avoid these problems? 
التوضيح
Stem cells are the precursor cells which...
Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
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