Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler

تمرين 5

Michaelis-Menten kinetics are used to describe intracellular reactions. Yet [E0] ª [S0]. In in
vitro batch reactors, the quasi-steady-state hypothesis does not hold for [E0] ª [S0]. The rapid
equilibrium assumption also will not hold. Explain why Michaelis-Menten kinetics and the
quasi-steady-state approximation are still reasonable descriptions of intracellular enzyme
reactions.