A continuous culture system is being constructed. The fermentation tank is to be 50,000 l in size and the residence time is to be 2 h. A continuous sterilizer is to be used. The unsterilized medium contains 11ec73a8_1d80_4bd3_b96d_97d06143e713_SM1185_11 spores/l. The value of 11ec73a8_1d80_4bd4_b96d_5b60f42a6c0c_SM1185_11 has been determined to be 11ec73a8_1d80_4bd5_b96d_91fc3f4cc990_SM1185_11 at 121∞C and 11ec73a8_1d80_4bd6_b96d_53d63f264c01_SM1185_11 at 140∞C. For each temperature (121∞C and 140∞C), determine the required res- idence time in the holding section so as to ensure that 99% of the time four weeks of continu- ous operation can be obtained without contamination (due to contaminants in the liquid medium).

Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler

النسخة 2الرقم المعياري الدولي: 9780130819086

Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler

النسخة 2الرقم المعياري الدولي: 9780130819086

تمرين 11

A continuous culture system is being constructed. The fermentation tank is to be 50,000 l in
size and the residence time is to be 2 h. A continuous sterilizer is to be used. The unsterilized
medium contains

spores/l. The value of

has been determined to be

at 121∞C
and

at 140∞C. For each temperature (121∞C and 140∞C), determine the required res-
idence time in the holding section so as to ensure that 99% of the time four weeks of continu-
ous operation can be obtained without contamination (due to contaminants in the liquid
medium).

التوضيح

موثّق

According to the given data a continuous...