Deck 19: Drugs Affecting the Immune System

Question 1

MMR vaccine is not recommended for pregnant women because:

A) Pregnant women do not build adequate immunity to the vaccine
B) There is a risk of the pregnant women developing measles encephalopathy
C) There is a risk of the fetus developing congenital rubella syndrome
D) Pregnant women can receive the MMR vaccine

Answer 1

There is a risk of the fetus developing congenital rubella syndrome

Question 2

Rh_o(D)immune globulin (RhoGAM)is given to:

A) Infants born to women who are Rh positive
B) Sexual partners of Rh positive women
C) Rh negative women after a birth,miscarriage,or abortion
D) Rh negative women at 36 weeks gestation

Answer 2

Rh negative women after a birth,miscarriage,or abortion

Question 3

Live attenuated influenza vaccine (FluMist)may be administered to:

A) All patients over 6 months of age
B) Patients between age 2 years and 49 years with no risk factors
C) Patients with a URI or asthma
D) Pregnant women

Answer 3

Patients between age 2 years and 49 years with no risk factors

Question 4

Tuberculin purified protein derivative (PPD):

A) Is administered to patients who are known tuberculin-positive reactors
B) May be administered to patients who are on immunosuppressives
C) May be administered 2 to 3 weeks after an MMR or varicella vaccine
D) May be administered the same day as the MMR and/or varicella vaccine

Question 5

Immune globulin serums (IGs):

A) Provide active immunity against infectious diseases
B) Are contraindicated during pregnancy
C) Are heated to above body temperature to kill most hepatitis,HIV,and other viruses such as parvovirus
D) Are derived from pooled plasma of adults and contain specific antibodies in proportion to the donor population

Question 6

Hepatitis B vaccine (HBV)is contraindicated in patients who:

A) Were born less than 32 weeks gestation (give first dose at age 6 months)
B) Are pregnant
C) Are on hemodialysis
D) Are allergic to yeast

Question 7

If the MMRV (measles,mumps,rubella,and varicella)combined vaccine is ordered to be given as the first MMR and varicella dose to a child the CDC recommends:

A) Parents be informed of the increased risk of fever and febrile seizures over the MMR plus varicella 2 shot regimen
B) Patients must also receive MMRV as the second dose of MMR and varicella in order to build adequate immunity
C) Patients be premedicated with acetaminophen 15 minutes before the vaccine is given
D) Patients should not be around pregnant women for the first 48 hours after the vaccine is given

Question 8

The rotavirus vaccine (RotaTeq,Rotarix):

A) Is a live vaccine that replicates in the small intestine,providing active immunity against rotavirus
B) Should not be administered to infants who are or may be potentially immunocompromised
C) Is not given to an infant who has a febrile illness (temperature greater than 100.5°F)
D) All of the above

Question 9

Attenuated vaccines are also known as:

A) Killed vaccines
B) Booster vaccines
C) Inactivated vaccines
D) Live vaccines

Question 10

Varicella vaccine is recommended to be given to patients who are:

A) HIV positive with a CD4+ T-lymphocyte percentage less than 15 percent
B) Taking corticosteroids (up to 2 mg/kg/day or less than 20 mg/day)
C) Pregnant
D) Immunocompromised

Question 11

Azathioprine has significant adverse drug effects,including:

A) Hypertension
B) Hirsutism
C) Risk of cancer
D) Gingival hyperplasia

Question 12

The reason that two MMR vaccines at least a month apart are recommended is:

A) The second dose of MMR "boosts" the immunity built from the first dose
B) Two vaccines 1 month apart is the standard dosing for all live virus vaccines
C) If the two MMR vaccine doses are given too close together there is a greater likelihood of severe localized reaction to the vaccine
D) Only 95% of patients are fully immunized for measles after the first vaccine,with 99% having immunity after two doses of MMR

Question 13

Human papillomavirus (HPV)vaccine (Gardasil,Cervarix):

A) Is a live virus vaccine that provides immunity to six strains of HPV virus
B) Has a common adverse effect of syncope within 15 minutes of giving the vaccine
C) Should not be given to males younger than age 12 years
D) May be given to pregnant women

Question 14

True contraindications to diphtheria,tetanus,and acellular pertussis (DTaP or Tdap)vaccine include:

A) Fever up to 104°F (40.5°C)after previous DTaP vaccine
B) Family history of seizures after DTaP vaccine
C) Adolescent pregnancy
D) Anaphylactic reaction with a previous dose

Question 15

Diane may benefit from cyclosporine (Sandimmune).Cyclosporin may be prescribed to:

A) Treat rheumatoid arthritis
B) Treat patients with corn allergy
C) Pregnant patients
D) Treat patients with liver dysfunction

Question 16

Influenza vaccine may be administered annually to:

A) Patients with egg allergy
B) Pregnant patients
C) Patients age 6 weeks or older
D) Patients with acute febrile illness

Question 17

Zoster vaccine (Zostavax)is:

A) A live varicella zoster vaccine from the same strain used to develop the varicella vaccine
B) Effective in preventing varicella zoster in patients of all ages
C) Recommended for patients age 40 to 80 who have had chickenpox
D) Administered at the same time as other live vaccines,as long as they are given the same day

Question 18

Hepatitis B immune globulin (HBIG)is administered to provide passive immunity to:

A) Infants born to HBsAg-positive mothers
B) Household contacts of hepatitis-B virus infected people
C) Persons exposed to blood containing hepatitis B virus
D) All of the above