Question 1

The nurse would evaluate that a client does not understand the proper use of allopurinol (Zyloprim)when the client states that it can be used for treatment of which of the following?&#10;A) Chronic gouty arthritis&#10;B) Acute attack of gout&#10;C) Urate nephropathy&#10;D) Renal calculi&#10;

Accepted Answer

Allopurinol is used for the treatment of chronic gouty arthritis and prevention of acute attacks of gout, but it is not used for the treatment of urate nephropathy or renal calculi. Therefore, if the client believes that allopurinol can be used for the treatment of these conditions, it shows a lack of understanding of the proper use of the drug.

Question 2

A client with gout who is beginning drug therapy with allopurinol (Zyloprim)asks the nurse how long it will take for the uric acid level in the bloodstream to return to normal.The nurse should explain that this will take approximately how long?

A) 3 to 5 days
B) 1 to 3 weeks
C) 3 to 6 weeks
D) 3 months or more

1 to 3 weeks

Accepted Answer

1 to 3 weeks

Question 3

The nurse who is preparing a teaching plan about the newly ordered drug allopurinol (Zyloprim)includes that it reduces uric acid&#10;A) by inhibiting the enzyme necessary to convert xanthine to uric acid.&#10;B) only in the blood.&#10;C) only in the urine.&#10;D) by promoting purine synthesis.&#10;

Accepted Answer

Allopurinol (Zyloprim) inhibits xanthine oxidase, which is the enzyme needed to convert xanthine to uric acid, resulting in reduced levels of uric acid in the blood and urine. It does not promote purine synthesis.

Question 4

The nurse who is explaining the effects of colchicine to a client would consider which of the following pieces of information?&#10;A) It causes decreased motility of leukocytes&#10;B) It aids the process of phagocytosis&#10;C) It increases uric acid metabolism&#10;D) It increases production of lactic acid&#10;

Accepted Answer

Colchicine causes decreased motility of leukocytes, which helps to reduce inflammation in conditions such as gout and familial Mediterranean fever. It does not aid phagocytosis or increase uric acid metabolism, and has no effect on production of lactic acid.

Question 5

The nurse would assess the client who is just beginning oral drug therapy with colchicine for which of the following adverse effects?&#10;A) Nausea and vomiting&#10;B) Flulike symptoms&#10;C) Tingling of the fingers and toes&#10;D) Alopecia&#10;

Accepted Answer

Nausea and vomiting are common adverse effects of colchicine, particularly when initiating therapy. Flulike symptoms and tingling of the fingers and toes may also occur, but they are less common. Alopecia is not a known adverse effect of colchicine.

Question 6

The nurse questions an order for which of the following medications that should be avoided while a client is taking allopurinol (Zyloprim)?&#10;A) Salicylates (Aspirin)&#10;B) Acetaminophen (Tylenol)&#10;C) Warfarin sodium (Coumadin)&#10;D) Hydrochlorothiazide (Thiazide)&#10;

Accepted Answer

The answer of The nurse questions an order for which...

Question 7

The nurse recommends which measure to ensure that the client with gout complies with the medication regimen?&#10;A) Take the medication on an empty stomach&#10;B) Take the medication between meals&#10;C) Drink a small amount of water with the medication&#10;D) Drink a large amount of water (3000 mL)while taking the medication&#10;

Accepted Answer

Drinking a large amount of water (3000 mL) while taking the medication is important to help prevent the formation of kidney stones, a potential complication of gout medication. Taking the medication on an empty stomach or between meals may also be recommended depending on the specific medication, but drinking enough water is universally important for gout management.

Question 8

The nurse explains to a client who has gout that the swelling associated with the current episode of gout may take how long to resolve?&#10;A) 4 hours&#10;B) 12 hours&#10;C) 1 to 2 days&#10;D) 3 days or more&#10;

Accepted Answer

Gout is a form of inflammatory arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness in one or more joints. The swelling associated with a gout attack can take several days to resolve, often 3 days or more, depending on the severity of the attack and the treatment initiated.

Question 9

As part of discharge instructions for a client with gout,the nurse includes which of the following in a list of items that would lead to an elevation in serum acid level?&#10;A) Mannitol&#10;B) Probenecid&#10;C) Alcohol&#10;D) Radiopaque dyes&#10;

Accepted Answer

Alcohol consumption can lead to an increase in serum acid level, exacerbating symptoms of gout. Mannitol, probenecid, and radiopaque dyes do not affect serum acid levels.

Question 10

The nurse explains to a client that allopurinol (Zyloprim)aids in the treatment of gout by its ability to do which of the following?&#10;A) Increase xanthine oxidase levels&#10;B) Decrease nitrogen synthesis&#10;C) Increase prostaglandin levels&#10;D) Decrease uric acid synthesis&#10;

Accepted Answer

Allopurinol works by inhibiting the enzyme xanthine oxidase, which is responsible for converting hypoxanthine to xanthine and then to uric acid. By inhibiting this enzyme, the production of uric acid is decreased, which helps to prevent the buildup of uric acid crystals in the joints that can cause gout.

Question 11

The nurse explains to a client with gout that at least how much time needs to elapse between courses of therapy with colchicine to avoid toxic drug accumulation?&#10;A) 1 day&#10;B) 3 days&#10;C) 5 days&#10;D) 7 days&#10;

Accepted Answer

The answer of The nurse explains to a client with...

Question 12

Assessment of the client on colchicine should include consideration of data leading to which of the following nursing diagnoses?&#10;A) Disturbed thought processes related to mood and mental changes&#10;B) Risk for infection related to medication-induced leukocytosis&#10;C) Risk for injury related to possible loss of balance and falls&#10;D) Altered self-concept related to an increase in weight&#10;

Accepted Answer

The answer of Assessment of the client on colchicine should...

Question 13

The nurse recommending a diet to enhance an alkaline urine that prevents calcium oxalate stones would suggest which of the following foods to the client?&#10;A) Prunes&#10;B) Plums&#10;C) Cranberries&#10;D) Apples&#10;

Accepted Answer

The answer of The nurse recommending a diet to enhance...

Question 14

The nurse determines that a client understands the effects of colchicine in the treatment of gout when the client states that the pain should be relieved how long after starting drug therapy?&#10;A) 4 hours&#10;B) 12 hours&#10;C) 1 to 2 days&#10;D) 3 to 5 days&#10;

Accepted Answer

The answer of The nurse determines that a client understands...

Question 15

A nurse teaches a client taking allopurinol (Zyloprim)to avoid which of the following foods to minimize the formation of calcium oxalate stones?&#10;A) Milk&#10;B) Peas&#10;C) Cranberries&#10;D) Molasses&#10;

Accepted Answer

The answer of A nurse teaches a client taking allopurinol...

Question 16

In addition to uric acid level,the nurse would place highest priority on assessing which of the following laboratory test results for a client with gout who is taking colchicine?&#10;A) Complete blood count&#10;B) Clotting times&#10;C) Serum electrolytes&#10;D) Urinalysis&#10;

Accepted Answer

The answer of In addition to uric acid level,the nurse...

Question 17

The nurse should ensure that which of the following juices is not on the breakfast tray of a client taking colchicine as treatment for gout?&#10;A) Apple&#10;B) Orange&#10;C) Grapefruit&#10;D) Pineapple&#10;

Accepted Answer

The answer of The nurse should ensure that which of...

Deck 34: Uricosuric Drugs