Deck 32: Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease

Question 1

The nurse is planning to administer an antacid to a patient diagnosed with PUD who will receive an H₂ antagonist at 8:00 AM.When is the most appropriate time for the nurse to provide the antacid to this patient?

A) With the H₂ antagonist
B) 30 minutes prior to the H₂ antagonist
C) 2 hours after the H₂ antagonist
D) Within an hour after the H₂ antagonist

Answer 1

2 hours after the H₂ antagonist

Question 2

The nurse is preparing to administer medications and notes that a patient has sucralfate ordered qid.When is the best time to administer this medication?

A) 1 hour before meals
B) With meals
C) 1 hour after meals
D) With a bedtime snack

Answer 2

1 hour before meals

Question 3

Which factor(s)prevent(s)breakdown of the body's normal defense barriers that protect against ulcer formation? (Select all that apply.)

A) Stomach pH
B) Prostaglandins
C) Intrinsic factor
D) Mucous cells
E) Hydrochloric acid

Answer 3

Prostaglandins
Mucous cells

Question 4

Cimetidine (Tagamet)is an example of which class of drug?

A) Protokinetic agent
B) Proton pump inhibitor
C) Histamine (H₂)receptor antagonist
D) Coating agent

Question 5

Which is a common adverse effect of magnesium-based antacid preparations?

A) Heartburn
B) Rebound indigestion
C) Constipation
D) Diarrhea

Question 6

Which are important nursing considerations when administering prokinetic agents? (Select all that apply.)

A) These agents are used to treat esophagitis associated with gastric reflux.
B) They are used to treat GERD when lifestyle changes and diet are ineffective.
C) They may be useful in treating nausea associated with chemotherapy treatment.
D) They may be administered intravenously.
E) Administer the medication to diabetic patients after meals.

Question 7

Which information will the nurse include when teaching a patient with renal failure about antacid therapy for treatment of heartburn? (Select all that apply.)

A) Taking magnesium-based antacids prevents diarrhea.
B) Magnesium-based antacids are preferred for patients with renal failure.
C) Aluminum hydroxide antacids exacerbate constipation.
D) If the patient has coffee-ground emesis or bloody stools,the frequency of antacids should be doubled.
E) Antacids neutralize gastric acid.

Question 8

Which explanation by the nurse is accurate to include when teaching a patient who is beginning therapy for gastroesophageal reflux disease (GERD)with metoclopramide?

A) "This medication decreases esophageal muscle tone to reduce reflux."
B) "Peristalsis is increased,so food is digested more quickly."
C) "Gastric emptying is delayed,so you may feel full for longer intervals."
D) "This medication is an antikinetic agent,so you may have difficulty with motor skills."

Question 9

A patient who is taking NSAIDs to treat arthritis asks the nurse why misoprostol has also been prescribed.Which explanation by the nurse is accurate?

A) NSAIDs often cause GI irritation that can result in peptic ulcers.
B) NSAIDs promote the production of prostaglandins and reduce the incidence of gastric irritation.
C) Antiulcer medications eradicate the presence of bacteria in the stomach that cause ulcers.
D) Drug interactions are prevented when antiulcer medications are used in combination with NSAIDs.

Question 10

Which factor(s)contribute(s)to the development of PUD? (Select all that apply.)

A) Cigarette smoking
B) Stress
C) Genetics
D) Excessive ingestion of milk products
E) H.pylori

Question 11

Which drug therapy is aimed at reducing gastric acid secretions? (Select all that apply.)

A) Prokinetic agents
B) Antacids
C) H₂ antagonists
D) Proton pump inhibitors
E) Coating agents

Question 12

Which organism or disorder is responsible for many cases of PUD?

A) H.pylori
B) Candida albicans
C) Escherichia coli
D) Herpes zoster

Question 13

The nurse is instructing a patient recently diagnosed with GERD.Which statement by the patient indicates a need for further teaching?

A) "I will avoid foods high in fat."
B) "I will eat small frequent meals and have a snack at bedtime."
C) "Orange juice may aggravate my symptoms."
D) "I will wait 2 hours after eating lunch before lying down for a nap."

Question 14

Which medication is used in the treatment of gastric reflux esophagitis and diabetic gastroparesis?

A) Metoclopramide
B) Misoprostol
C) Pantoprazole
D) Ranitidine

Question 15

The nurse is discussing dietary and lifestyle changes with a patient diagnosed with GERD.When reviewing necessary modifications,the nurse will include information regarding: (Select all that apply.)

A) limiting coffee intake to 2 cups/day.
B) smoking cessation.
C) avoiding NSAIDs.
D) decreasing protein foods.
E) using nonfat milk.

Question 16

A patient taking misoprostol (Cytotec)to treat a gastric ulcer reports recurrent diarrhea.The nurse should encourage this patient to:

A) immediately discontinue misoprostol (Cytotec).
B) take with a magnesium-containing antacid.
C) omit fresh fruits from diet.
D) take medication with meals.

Question 17

Which is considered an acceptable time frame for a patient with gastric distress to self-medicate with over-the-counter antacids?

A) Hours
B) Days
C) Weeks
D) Months

Question 18

A patient with PUD asks the nurse about the action of prokinetic medications.Which explanation by the nurse is accurate?

A) It blocks the formation of hydrochloric acid,reducing irritation of the gastric mucosa.
B) It increases the lower esophageal sphincter muscle pressure and peristalsis.
C) It reduces the secretion of saliva,hydrochloric acid,pepsin,bile,and other enzymatic fluids.
D) It decreases the volume of hydrochloric acid produced,increasing the gastric pH.

Question 19

A postoperative appendectomy patient has a nasogastric tube and wonders why the previous nurse told him that he was receiving an IV "ulcer-preventing" medication called ranitidine.The patient states that he has never had any stomach problems in his life.Which is the best response by the nurse?

A) "This medication will cause the pH in your stomach to drop."
B) "This medication helps coat your stomach while the nasogastric tube is in place."
C) "Because you are not eating after surgery,this medication will help reduce the hydrochloric acid your stomach is still secreting."
D) "The nasogastric tube will cause peptic ulcer disease.This medication will help prevent that."