Deck 14: Drugs Used to Treat Neurodegenerative Disorders

Question 1

The nurse is providing information to a patient recently prescribed entacapone.Which statement is correct?

A) This medication is not to be taken with carbidopa levodopa.
B) Dosage is adjusted according to the patient's response.
C) There will be fewer incidences of dopaminergic effects,such as confusion.
D) This medication increases the production of dopamine in the brain.

Answer 1

Dosage is adjusted according to the patient's response.

Question 2

Parkinson's disease has which characteristic symptom(s)? (Select all that apply.)

A) Muscle tremors
B) Posture alterations
C) Muscle flaccidity
D) Tachycardia
E) Slow body movement

Answer 2

Muscle tremors
Posture alterations
Slow body movement

Question 3

The nurse is teaching a patient with Parkinson's disease about levodopa.Which statement by the nurse is accurate regarding drug administration?

A) "Take this medication in between meals."
B) "Take this medication at bedtime to prevent dizziness."
C) "Take this medication when your tremors get worse."
D) "Take this medication with food or antacids to reduce GI upset."

Answer 3

"Take this medication with food or antacids to reduce GI upset."

Question 4

The nurse is preparing to begin administration of apomorphine to a patient.Before administering,the nurse will perform a baseline assessment of the patient's: (Select all that apply.)

A) mobility.
B) orientation.
C) intellectual ability.
D) alertness.
E) vital signs.

Question 5

Which adverse effects associated with levodopa therapy would support the nursing diagnosis risk for injury?

A) Nausea and vomiting
B) Orthostatic hypotension
C) Anorexia and depression
D) Tachycardia and palpitations

Question 6

A patient taking rasagiline is assessed by the nurse to have a lasting significant increase in blood pressure.When reviewing the patient's current list of medications,the nurse decides to hold the next dose of:

A) dextromethorphan.
B) levodopa.
C) ciprofloxacin.
D) Valium.

Question 7

What is the rationale for administering levodopa instead of dopamine for treatment of Parkinson's disease?

A) Dopamine does not cross the blood-brain barrier when administered orally.
B) Levodopa is much less expensive.
C) The half-life of dopamine is too short.
D) Dopamine has too many reactions with other medications.

Question 8

The nurse is providing education to a patient recently placed on selegiline disintegrating tablets.Which statement by the patient indicates a need for further teaching?

A) "This medication will help slow the development of symptoms."
B) "I will place the tablet on my tongue before breakfast."
C) "I may need to use a stool softener for constipation."
D) "I should not push the tablet through the foil."

Question 9

The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 week ago.The patient has a history of coronary artery disease and takes an antihypertensive and aspirin.Which information would support the need for a reduction in medication dosage by the healthcare provider?

A) Constipation
B) Brownish orange urine
C) Drowsiness
D) Dizziness

Question 10

What is the pharmacologic action of entacapone,a potent catechol O methyl transferase (COMT)inhibitor?

A) Slows the deterioration of dopaminergic nerve cells.
B) Inhibits the relative excess of dopaminergic activity.
C) Reduces the destruction of dopamine in peripheral tissues.
D) Enhances the cholinergic symptoms of Parkinson's disease.

Question 11

Which vitamin will reduce the therapeutic effects of levodopa?

A) A
B) B₆
C) C
D) D

Question 12

Which cholinergic symptoms of Parkinson's disease are reduced with anticholinergic drugs?

A) Cognitive impairments
B) Rigidity
C) Tremors and drooling
D) Postural abnormalities

Question 13

When a patient taking a monoamine oxidase B inhibitor receives his dietary tray,the nurse knows to remove the:

A) cheese.
B) eggs.
C) bread.
D) coffee.

Question 14

Dopamine agonists have been linked with which adverse effects in patients with Parkinson's disease?

A) Oculogyric crisis
B) Tardive dyskinesia
C) Sudden sleep events
D) Akathisia