Deck 29: Treatment of Psychotic Disorders

Question 1

Extrapyramidal symptoms occur with antipsychotics due to:

A) Inhibition of receptors in the mesolimbic region of the brain
B) A compensatory response in the mesolimbic region due to receptor blockade
C) Blockade of muscarinic cholinergic receptors
D) Blocking of dopamine receptors in the basal ganglia
E) Up regulation of dopamine receptors

Answer 1

Blocking of dopamine receptors in the basal ganglia

Question 2

Atypical antipsychotics differ from typical antipsychotics in that:

A) Atypical antipsychotics have a smaller therapeutic window
B) Atypical antipsychotics block more D₂ receptors than typical antipsychotics
C) Atypical antipsychotics block 5-HT_2A as well as D₂ receptors
D) Atypical antipsychotics have a higher incidence of adverse effects
E) Atypical antipsychotics have no known side effects

Answer 2

Atypical antipsychotics block 5-HT_2A as well as D₂ receptors