Deck 14: Antineoplastic Drugs

Question 1

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Used to prevent allergic reactions to other agents

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Answer 1

Hormones

Question 2

Match the corresponding term with its definition.
Reduction in red blood cells

A)Pancytopenia
B)Thrombocytopenia
C)Leukopenia
D)Anemia

Answer 2

Anemia

Question 3

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Includes monoclonal antibodies and interferons

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Answer 3

Biological therapies

Question 4

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
May be implanted, injected or attached to MABs for targeted treatment

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 5

Antineoplastic

A)Alleviation of symptoms
B)Reproducing rapidly
C)Destructive to cells
D)Against new tissue formation
E)Decrease the production of antibodies

Question 6

Match the corresponding term with its definition.
Reduction in platelets

A)Pancytopenia
B)Thrombocytopenia
C)Leukopenia
D)Anemia

Question 7

Cytotoxic:

A)Alleviation of symptoms
B)Reproducing rapidly
C)Destructive to cells
D)Against new tissue formation
E)Decrease the production of antibodies

Question 8

The administration of chemotherapy includes ___________.

A) frequently modifying and individualizing treatment according to the patient's response
B) adjusting therapy based on the client's weight and age
C) administration of standardized therapy doses on a continuous basis
D) treating side effects as they appear

Question 9

Match the corresponding term with its definition.
Reduction in white blood cells

A)Pancytopenia
B)Thrombocytopenia
C)Leukopenia
D)Anemia

Question 10

Immunosuppressive

A)Alleviation of symptoms
B)Reproducing rapidly
C)Destructive to cells
D)Against new tissue formation
E)Decrease the production of antibodies

Question 11

Palliative

A)Alleviation of symptoms
B)Reproducing rapidly
C)Destructive to cells
D)Against new tissue formation
E)Decrease the production of antibodies

Question 12

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Dose-limited, used in wide variety of malignancies

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 13

Match the corresponding term with its definition.
Reduction in all blood cells

A)Pancytopenia
B)Thrombocytopenia
C)Leukopenia
D)Anemia

Question 14

Proliferating

A)Alleviation of symptoms
B)Reproducing rapidly
C)Destructive to cells
D)Against new tissue formation
E)Decrease the production of antibodies

Question 15

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Plant alkaloid

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 16

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Less harmful to normal cells includes signal transduction inhibitors

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 17

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Rapidly proliferating neoplasms

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 18

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Interfere with the DNA of a cancer cell

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 19

Antineoplastic agents are classified into nine major categories.Match the category with the corresponding label or characteristic of each.
Preventive and therapeutic types; boost natural immunity against infectious agents

A)Alkylating agents
B)Hormones
C)Biological therapies
D)Mitotic inhibitors
E)Antimetabolites
F)Antitumor antibiotics
G)Radioactive isotopes
H)Targeted cancer therapies
I)Vaccines

Question 20

Chemotherapy administration involves ____________.

A) a standardized treatment that is not altered after treatment has begun
B) an intermittent schedule
C) treating side effects as they appear
D) single-agent therapy

Question 21

Chemotherapy agents may cause a suppression in bone marrow, resulting in _______.

A) thrombocytopenia
B) leukopenia
C) pancytopenia
D) anemia
E) All of the above.

Question 22

Peripheral nerve damage is most commonly associated with which group of chemotherapy drugs?

A) Antineoplastics
B) Mitotic inhibitors
C) Antitumor antibiotics
D) Alkylating agents

Question 23

Side effects associated with interferons may include __________.

A) flu-like symptoms
B) depression
C) GI symptoms
D) All of the above.

Question 24

Intrathecal administration of mitotic inhibitors _______.

A) may be preferred over IV to enhance absorption
B) is a last resort when IV access cannot be obtained
C) is not recommended in children
D) is fatal and is never a possible route

Question 25

Agatha is receiving palliative chemotherapy, which is intended to ____.

A) halt tumor growth
B) prevent recurrence
C) prevent metastases
D) alleviate symptoms

Question 26

Hormone therapies are frequently used with other chemotherapy agents to _________.

A) treat and prevent nausea
B) prevent alopecia and fatigue
C) treat and prevent osteoporosis
D) prevent Cushingoid features

Question 27

Which of the following is true of Tamoxifen?

A) Is a selective estrogen-receptor modifier (SERM)
B) May be used as primary therapy and as palliative treatment
C) Used in both men and women
D) Serious adverse effects are rare.
E) All of the above.

Question 28

Patient education for families of patients undergoing cancer treatments should __________.

A) not include discussion regarding side effects
B) stress the importance of avoiding oral food and fluid intake to prevent nausea
C) indicate that once therapy has begun it cannot be discontinued
D) include the importance of aseptic technique and good oral hygiene

Question 29

Side effects associated with monoclonal antibodies may be avoided by ________.

A) premedication with corticosteroids
B) giving with a full glass of water after a full meal
C) premedication with acetaminophen, diphenhydramine, or meperidine
D) administering deep into a large muscle

Question 30

By what route are monoclonal antibodies administered?

A) Intrathecally
B) Orally
C) Intravenously
D) Intramuscularly

Question 31

Rylie is an oncology nurse who is trying to conceive a baby.Is it safe for her to administer cytotoxic chemotherapy?

A) Yes, as long as she uses standard chemotherapeutical administration precautions.
B) Possibly.She may be able to administer select medications depending on the type of cytotoxic drug being administered.
C) Yes, as long as she does not handle them at the time she is ovulating.
D) No.Women who are pregnant, breast-feeding, or actively trying to conceive a child should not care for patients receiving cytotoxic drugs.

Question 32

Antiandrogen hormonal therapies are used to treat _______.

A) breast cancer
B) bladder cancer
C) prostate cancer
D) uterine cancer

Question 33

The primary side effect experienced by patients following radioimmunotherapy is ________.

A) heart failure
B) ascites
C) decreased blood count
D) None of the above.

Question 34

Health care workers should observe what type of precautions while caring for patients receiving radioactive isotopes?

A) Universal precautions because the isotope is retained within the patient's body and offers no special risk to the health care worker.
B) Additional care to prevent contact with any of the patient's body fluids as well as special handling of linens to protect the health care worker.
C) Gloves need only be worn when administering the isotope.
D) Only masks are necessary in order to prevent transmission of respiratory infections.

Question 35

Patients being treated with antineoplastic drugs and their families should be instructed ________.

A) to omit discussion regarding side effects, in order to avoid a self-filling prophecy
B) that foods will be allowed only based on client's caloric needs
C) to avoid brushing teeth as it may cause bleeding
D) to observe for bruises and for bleeding in stools, urine, and gums, reporting any evidence of such to medical personnel

Question 36

A maximum lifetime dose has been established for this antitumor antibiotic given for breast cancer due to cardiotoxicity.

A) Interferon
B) Vincristine
C) Vinorelbine (Navelbine)
D) Doxorubicin (Adriamycin)

Question 37

Bone marrow suppression is a side effect that may result from several types of chemotherapy agents.Which of the following is NOT an indicator of bone marrow suppression?

A) Nausea
B) Susceptibility to infection
C) Prolonged bleeding times
D) Increased bruising

Question 38

Precautions that should be taken while caring for patients receiving cytotoxic drugs include _______.

A) nothing more than "Universal Precautions"
B) persons who are pregnant, breast-feeding, or actively trying to conceive should not care for clients receiving cytotoxic drugs
C) ordinary disposal of syringes, IV tubing and bags, or any other contaminated materials
D) using gloves when handling cytotoxic drugs

Question 39

Important responsibilities of the health care workers involved in the administration of antineoplastic agents include __________.

A) checking intravenous sites with great care to ensure antineoplastic agents do not infiltrate, causing extreme tissue damage and necrosis
B) keeping the patients NPO in order to avoid nausea and vomiting
C) making sure that only the physician performs all teaching
D) relying on the physician to perform all of the assessments for infection

Question 40

Biological therapies are given to ______.

A) stimulate the body's immune system to work against cancer cells
B) combat side effects of chemotherapy agents such as bone marrow suppression
C) Target cancer cells and spare normal cells.
D) All of the above.

Question 41

Your friend Reanna asks you about cancer prevention methods that go beyond lifestyle changes.You inform her about Gardasil and Cervarix, which protect against infection by two high-risk types of human papillomavirus (HPV).What percentage of cervical cancers, worldwide, are associated with those two types of HPV?

A) 95%
B) 60%
C) 80%
D) 70%

Question 42

Three-year-old Landon has painful sores in his mouth caused by chemotherapy for leukemia.What instructions should his parents be given about oral hygiene?

A) Brush frequently and vigorously to reduce the risk of infection.
B) Use an alcohol-based mouthwash for its antibacterial properties.
C) Use swabs to avoid further damage.
D) Brush and use floss twice a day to promote cleanliness.

Question 43

Your best friend is diagnosed with lymphoma and asks you about what she's read about the side effects of treatments, particularly gastrointestinal effects and hair loss.You explain to her that many drugs used in the treatment of cancer have effects on the gastrointestinal system and hair because they are especially toxic to cells that are ____.

A) DNA-dependent
B) particularly complex
C) slow to reproduce
D) rapidly proliferating

Question 44

Bryant has skin cancer and is being treated with an antimetabolite, which routes are available for administration ____.

A) IV only
B) IV, topical, and oral forms are available
C) Oral and topical
D) Oral only

Question 45

Macy's chemotherapy has left her so anemic and prone to infections that treatment must be temporarily halted.What type of drug might Macy be prescribed to help her body produce bone marrow stem cells that divide and develop into red and white blood cells, and platelets?

A) Signal transduction inhibitor
B) Colony-stimulating factor
C) Vaccine
D) Monoclonal antibody

Question 46

Sebastian has chronic myelogenous leukemia and is being given imatinib (Gleevec).Imatinib blocks specific enzymes and growth factor receptors that affect cancer cell proliferation and belongs to the class of drugs called ____.

A) signal transduction inhibitors
B) mitotic inhibitors
C) antitumor antibiotics
D) monoclonal antibodies

Question 47

Darian is being treated for lymphoma and invariably experiences nausea and vomiting from his chemotherapy.What medication might be useful in minimizing these side effects?

A) Sipuleucel-T
B) Tositumomab
C) Imatinib
D) Ondansetron