Deck 11: The Nervous System: Autonomic and Motor Systems

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Question
Which of the following descriptions of collateral ganglia is TRUE?

A)Collateral ganglia are part of the somatosensory system, located off of the afferent neuron just prior to entering the spinal cord dorsal horn.
B)Collateral ganglia are part of the somatic nervous system, located where the motor neuron leaves the ventral horn.
C)Collateral ganglia are located within a chain just outside the spinal cord and are the sites of communication between sympathetic preganglionic neurons and postganglionic neurons.
D)Collateral ganglia are in the sympathetic nervous system but distinct from the sympathetic chain, and they function as a site of communication between sympathetic preganglionic neurons and postganglionic neurons.
E)Collateral ganglia are located within the effector organs and are the sites of communication between parasympathetic preganglionic neurons and postganglionic neurons.
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Question
Which of the following contributes to the ability of the sympathetic nervous system to produce widespread responses within the body?

A)Several preganglionic neurons activate a single postganglionic neuron.
B)Multiple preganglionic neurons innervate each ganglion, sending out individual postganglionic neurons.
C)One preganglionic neuron can activate only one postganglionic neuron.
D)One preganglionic neuron sends collaterals to multiple ganglia, affecting multiple postganglionic neurons.
E)One postganglionic neuron branches into many collaterals that affect multiple organs.
Question
Which of the following is located between the invaginations of the motor end plate of a neuromuscular junction?

A)nicotinic receptors
B)fi2 receptors
C)fi3 receptors
D)acetylcholinesterase
E)muscarinic receptors
Question
What are swellings of postganglionic autonomic axons from which neurotransmitters are released called?

A)sympathetic trunks
B)ganglia
C)neuromuscular junctions
D)varicosities
E)parasympathetic chains
Question
Which of the following statements is TRUE of communication across the neuromuscular junction?

A)Synaptic communication to the muscle cell can be excitatory or inhibitory.
B)The end- plate potential is always of sufficient magnitude to depolarize the muscle cell to threshold to initiate an action potential.
C)Acetylcholine released from a motor neuron binds to muscarinic cholinergic receptors.
D)Acetylcholinesterase located in mitochondria of the motor neuron degrades acetylcholine to acetate and choline.
E)Acetylcholinesterase located in the cytosol of the motor neuron degrades acetylcholine to acetate and choline.
Question
What is the correct order for the steps of synaptic transmission at the motor end plate? 1. Acetylcholine binds to postsynaptic receptors.
2) Acetylcholine is released by exocytosis.
3) A graded depolarization is produced.
4) An action potential is produced on the muscle cell membrane.
5) Channels that primarily allow diffusion of sodium are opened.
6) Voltage- dependent calcium channels on the plasma membrane open.
7) An action potential arrives at the axon terminal.

A)7, 6, 2, 1, 5, 3, 4
B)7, 6, 2, 1, 3, 4, 6
C)7, 5, 2, 1, 3, 4, 6
D)6, 7, 2, 1, 3, 5, 4
E)5, 7, 6, 2, 1, 4, 3
Question
The presence of within varicosities initiates the release of neurotransmitter.

A)mechanically- gated Ca2+ channels
B)voltage- gated Ca2+ channels
C)mechanically- gated Na+ channels
D)voltage- gated Na+ channels
E)voltage- gated K+ channels
Question
Binding of norepinephrine or epinephrine to a(n)receptor will activate an inhibitory G protein which decreases the activity of adenylate cyclase and therefore cAMP synthesis while the binding of these two neurotransmitters to a receptor will do the exact opposite.

A)fi2 : fi1
B)a2 : a1
C)a1 : a2
D)fi1 : fi2
E)a2 : fi1
Question
Where do the preganglionic neurons of the sympathetic nervous system emerge from the spinal cord?

A)sacral region only
B)thoracic region only
C)lumbar and sacral regions
D)thoracic and lumbar regions
E)lumbar region only
Question
What enzyme degrades the neurotransmitter released from varicosities of parasympathetic postganglionic neurons?

A)choline acetyl transferase
B)catechol- O- methyltransferase only
C)monoamine oxidase only
D)catechol- O- methyltransferase and monoamine oxidase
E)acetylcholinesterase
Question
The change in membrane potential that occurs in skeletal muscle cells in response to acetylcholine binding to its receptors is called a(n)

A)repolarizing potential.
B)refractory period.
C)inhibitory post synaptic potential.
D)end- plate potential.
E)hyperpolarizing potential.
Question
Propranolol is a non- selective fi adrenergic receptor antagonist. It would be appropriate for a doctor to prescribe propranolol to treat

A)low blood pressure.
B)peptic ulcers.
C)myasthenia gravis.
D)hypertension.
E)asthma.
Question
At rest, what is the relative contribution of the sympathetic and parasympathetic nervous systems to the regulation of homeostasis?

A)Only the sympathetic system is active.
B)Only the parasympathetic system is active.
C)Both systems are active but the parasympathetic predominates.
D)Both systems are active but the sympathetic predominates.
E)Neither system is active.
Question
The somatic nervous system regulates the activity of

A)skeletal muscle.
B)many organs.
C)the cardiovascular system.
D)endocrine organs.
E)the kidneys.
Question
Actions at which class of adrenergic receptor generally have inhibitory effects?

A)a1
B)fi1
C)nicotinic
D)a1 and fi1
E)fi2
Question
With respect to their innervation, individual skeletal muscle fibers (cells)are innervated by

A)a single motor neuron.
B)multiple motor neurons.
C)a single motor neuron and autonomic neuron.
D)multiple motor neurons and autonomic neurons.
E)a single motor neuron and multiple autonomic neurons.
Question
The cranial nerve that innervates most of the viscera in the thoracic and abdominal cavities is the

A)IX, or glossopharyngeal nerve.
B)VII, or facial nerve.
C)X, or vagus nerve.
D)III, or oculomotor nerve.
E)VIII, or vestibulocochlear nerve.
Question
One of the adaptations that occur to muscles due to exercise is that contractions become stronger and steadier over time even with no change in muscle mass. Which statement below best explains why muscle contractions may become stronger?

A)The skeletal muscle contraction is enhanced by an increased input from the sympathetic nervous system.
B)Motor neurons are activated more rapidly to generate a stronger muscle contraction.
C)The action potentials sent by the motor neurons get larger and last longer to produce more force in the muscles.
D)More motor neurons are made so that more action potentials can be sent down to the muscles.
E)Muscle fibers reflexively start generating force even before the motor neurons send action potentials.
Question
What area of the brain initiates the fight- or- flight response by producing widespread activation of the sympathetic nervous system?

A)limbic system
B)hypothalamus
C)cerebellum
D)brainstem
E)amygdala
Question
What is the neurotransmitter released from motor neurons?

A)dopamine
B)acetylcholine
C)GABA
D)epinephrine
E)norepinephrine
Question
Parasympathetic preganglionic neurons release the neurotransmitter ; sympathetic preganglionic neurons release the neurotransmitter _ .

A)acetylcholine : norepinephrine
B)epinephrine : norepinephrine
C)norepinephrine : norepinephrine
D)norepinephrine : acetylcholine
E)acetylcholine : acetylcholine
Question
Which of the following best describes the general arrangement of the efferent limb of the autonomic nervous system?

A)one neuron
B)two neurons in parallel
C)two neurons in series
D)three neurons in series
E)three neurons in parallel
Question
Myasthenia gravis primarily affects women and its defining characteristic is fatigue of unusually rapid onset and severity following the use of certain muscle groups. What symptoms below best allude to the set of muscles affected by this disease?

A)difficulty moving the joints of the fingers and toes
B)relaxed bladder causing frequent urination
C)difficulty speaking, difficulty swallowing, and drooping eyelids
D)difficulty walking due to fatigue in the major muscles of the legs
E)difficulty in fine motor control of the fingers, especially the thumb
Question
The opening of a cation channel that allows both Na+ and K+ to move through will cause the membrane to _ _ because of the _.

A)depolarize : greater K+ electrochemical gradient as compared with Na+
B)hyperpolarize : greater K+ electrochemical gradient as compared with Na+
C)depolarize : greater Na+ electrochemical gradient as compared with K+
D)not change : same electrochemical gradient for K+ and Na+
E)hyperpolarize : greater Na+ electrochemical gradient as compared with K+
Question
Students who suffer from test anxiety often have some of the following symptoms: the need for frequent urination, dilated pupils, and a dry mouth. What branch of the autonomic nervous system would cause these symptoms?

A)enteric
B)somatic
C)voluntary
D)sympathetic
E)parasympathetic
Question
What is the primary mode of action of curare?

A)It causes the degradation of the enzyme acetylcholinesterase.
B)It decreases the amount of acetylcholine released from the synaptic terminal.
C)It decreases the number of functional receptors on the muscle cell by the process of phagocytosis, which impairs the ability of neurons to respond to acetylcholine.
D)It blocks communication at the neuromuscular junction by preventing acetylcholine from binding to nicotinic cholinergic receptors.
E)It blocks the sodium channels in the axon of the presynaptic axon.
Question
Which statement best describes the results of the autoimmune disease myasthenia gravis?

A)Communication at the neuromuscular junction is blocked by preventing acetylcholine from binding to nicotinic cholinergic receptors.
B)There is a decrease in the amount of acetylcholine released from the synaptic terminal.
C)A decrease in the number of functional receptors on the muscle cell surface impairs its ability to respond to acetylcholine.
D)There is degradation of the enzyme acetylcholinesterase.
E)There is blocking of sodium channels in the axon of the presynaptic axon.
Question
Located entirely within the autonomic ganglia, cells that modulate the flow of information to the target organ are called neurons.

A)ganglionic
B)intrinsic
C)intraganglionic
D)preganglionic
E)postganglionic
Question
Where are most of the autonomic nervous system control centers located?

A)brainstem
B)frontal lobe
C)limbic system
D)thalamus
E)spinal cord
Question
Scopolamine is a muscarinic antagonist that acts by blocking muscarinic acetylcholine receptors. Although it is not clear how scopolamine prevents nausea and vomiting due to motion sickness, which statement below best describes the mechanism of action for this drug?

A)Scopolamine works by preventing calcium influx at the axon terminal, therefore preventing the release of neurotransmitter.
B)Scopolamine works on the optic nerve blocking sodium channels so that the sight of motion does not make an individual sick.
C)Scopolamine causes chloride channels to open causing a subthreshold graded potential in the soma of the cell and, therefore, no action potential is ever generated that may cause motion sickness.
D)Scopolamine prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine.
E)Scopolamine breaks down acetylcholine in the synaptic cleft, therefore blocking the drug from entering the neuron.
Question
The autonomic nervous system innervates all the following effector organs and tissues EXCEPT

A)skeletal muscles.
B)adipose tissues.
C)endocrine glands.
D)cardiac muscles.
E)exocrine glands.
Question
Parasympathetic preganglionic neurons travel in what nerves?

A)pelvic nerves only
B)spinal nerves only
C)cranial nerves only
D)cranial and spinal nerves
E)cranial and pelvic nerves
Question
In what class of autonomic neuron and within what organelle is the enzyme monoamine oxidase located?

A)smooth ER of parasympathetic postganglionic neurons
B)mitochondria of sympathetic postganglionic neurons
C)lysosomes of sympathetic preganglionic neurons
D)synaptic vesicles of sympathetic postganglionic neurons
E)Golgi apparatus of parasympathetic postganglionic neurons
Question
Adrenergic receptors with the greatest affinity for epinephrine are receptors.

A)alpha 2
B)beta 1
C)beta 3
D)beta 2
E)alpha 1
Question
Preganglionic and postganglionic sympathetic neurons are anatomically arranged in what three patterns?

A)sympathetic, parasympathetic, and involuntary nervous systems
B)sympathetic chains, those that innervate the adrenal medulla, and collateral ganglia
C)nicotinic ganglia, adrenergic ganglia, and cholinergic ganglia
D)alpha, gamma, and beta cells
E)visceral, systemic, and cardiovascular
Question
Which of the following is indicative of the relative release of catecholamines from the adrenal medulla?

A)80% epinephrine : 20% norepinephrine
B)100% acetylcholine
C)80% norepinephrine : 20% dopamine
D)80% norepinephrine : 20% epinephrine
E)80% epinephrine : 20% dopamine
Question
fi2 adrenergic receptor agonists are used to treat acute asthma symptoms by eliciting a response similar to , which has a greater affinity for fi2 receptors and leads to dilation of the respiratory pathways.

A)atropine
B)epinephrine
C)cyclic AMP
D)norepinephrine
E)acetylcholine
Question
Sympathetic ganglia that are linked together and run in parallel on either side of the spinal column are called

A)collateral ganglia.
B)gray ramus.
C)sympathetic chains or trunks.
D)lateral horns.
E)white ramus.
Question
People who have done a lot of endurance training can have a resting heart rate of 50 beats per minute compared to the normal resting heart rate of 70- 80 beats per minute. This decreased heart rate in trained individuals is the partly result of

A)endorphins released from the brain which have an inhibitory effect on heart rate.
B)parasympathetic activity becoming more active and sympathetic activity becoming less active at rest.
C)sympathetic activity becoming more active and parasympathetic activity becoming less active at rest.
D)decreases in both sympathetic and parasympathetic activity.
E)increases in both sympathetic and parasympathetic activity.
Question
Which of the following physiological responses is associated with an elevation in parasympathetic nervous system activity?

A)shifting blood flow away from the gastrointestinal tract
B)increased contractile force of the heart
C)enhanced absorption of nutrients
D)enhanced mobilization of energy stores
E)increased heart rate
Question
Parasympathetic postganglionic neurons release the neurotransmitter ; sympathetic postganglionic neurons release the neurotransmitter .

A)norepinephrine : norepinephrine
B)acetylcholine : norepinephrine
C)epinephrine : norepinephrine
D)norepinephrine : acetylcholine
E)acetylcholine : acetylcholine
Question
What is the graded change in membrane potential that occurs at the motor end plate of skeletal muscle called?

A)inhibitory postsynaptic potential
B)muscarinic potential
C)end- plate potential
D)adrenergic potential
E)action potential
Question
Which of the following physiological responses is associated with elevated sympathetic nervous system activity?

A)increased contractile force of the heart
B)inhibition of cardiovascular function
C)enhanced digestion
D)decreased heart rate
E)enhanced absorption of nutrients
Question
The most abundant neurotransmitter in the peripheral nervous system is acetylcholine.
Question
How does latroxin, the venom of the black widow spider, cause muscle spasms and rigidity?

A)It stimulates acetylcholine release from motor neurons.
B)It inhibits acetylcholine release from motor neurons.
C)It stimulates acetylcholine release from autonomic preganglionic neurons.
D)It blocks nicotinic cholinergic receptors.
E)It inhibits the degradation of acetylcholine at all synapses.
Question
Postganglionic neurons of the autonomic nervous system release neurotransmitter from

A)neuromuscular junction.
B)axon hillock.
C)varicosities.
D)somas.
E)dendrites.
Question
The autonomic nervous system consists of efferent pathways with two peripheral neurons that travel in series from the central nervous system to the effector organ.
Question
Atropine, first derived from the Atropa belladonna plant, is a nicotinic receptor antagonist.
Question
Dual innervation of organs by the autonomic nervous system refers to the observation that

A)autonomic and somatic neurons innervate all organs.
B)both sympathetic and parasympathetic neurons innervate most organs.
C)autonomic neurons that innervate each target organ originate from two ganglia.
D)autonomic innervation involves preganglionic and postganglionic neurons.
E)two postganglionic sympathetic neurons innervate each target organ.
Question
Binding of acetylcholine to receptors will activate a G protein.

A)adrenergic
B)nicotinic
C)muscarinic
D)somatostatic
E)cholinergic
Question
Sympathetic preganglionic neurons exit the spinal cord via the _ root, and then join the spinal nerve. They leave the spinal nerve and enter the ganglion via the _ ramus. Most of the postganglionic fibers return to the spinal nerve via the _ ramus.

A)ventral : gray : white
B)dorsal : white : gray
C)dorsal : gray : white
D)ventral : white : gray
E)dorsal : gray: gray
Question
Which of the following endocrine glands is innervated by sympathetic preganglionic neurons?

A)pancreas
B)thyroid gland
C)anterior pituitary
D)adrenal cortex
E)adrenal medulla
Question
When the body is stressed, what is the relative contribution of the sympathetic and parasympathetic nervous systems to the regulation of homeostasis?

A)Only the parasympathetic system is active.
B)Only the sympathetic system is active.
C)Both systems are active but the parasympathetic predominates.
D)Both systems are active but the sympathetic predominates.
E)Neither system is active.
Question
Parasympathetic neurons from which cranial nerve innervate most of the viscera in the thoracic and abdominal cavities?

A)I
B)III
C)VII
D)IX
E)X
Question
Where in the central nervous system do the preganglionic neurons of the parasympathetic nervous system originate?

A)thoracic region of the spinal cord only
B)thoracic and lumbar regions of the spinal cord
C)brainstem and sacral region of the spinal cord
D)sacral region of the spinal cord only
E)lumbar region of the spinal cord only
Question
The somatic nervous system is often referred to as the system.

A)craniosacral
B)unconscious
C)voluntary
D)neuromuscular
E)involuntary
Question
Binding of acetylcholine to receptors causes by opening channels that primarily permit sodium to permeate the membrane.

A)nicotinic : a depolarization
B)nicotinic : no change in membrane potential
C)muscarinic : a hyperpolarization
D)muscarinic : a depolarization
E)nicotinic : a hyperpolarization
Question
Where on skeletal muscle is the highest density of nicotinic receptors?

A)motor end plate
B)dendrites
C)axon hillock
D)terminal bouton
E)motor unit
Question
The somatic nervous system provides both excitatory and inhibitory signals to skeletal muscle.
Question
Compared to norepinephrine, epinephrine has a greater affinity for what type of receptor?

A)muscarinic
B)nicotinic
C)fi2
D)fi1
E)a1
Question
For skeletal muscle to relax, the neural stimulation must decrease.
Question
Physiological stressors will cause parasympathetic nervous system activity to increase.
Question
The autonomic nervous system is also known as the involuntary nervous system.
Question
Describe the synaptic junctions between the neurons of the autonomic and somatic nervous systems and their effector organs.
Question
Norepinephrine is one of the more important neurotransmitters of the peripheral nervous system. Identify the branches of the peripheral nervous system for which norepinephrine is the neurotransmitter and describe the receptors responsible for responding to norepinephrine. Include the mechanisms whereby these receptors transduce the response to norepinephrine.
Question
The nature of a response from the sympathetic nervous system is determined by the anatomy of this system. Describe the general structure of the sympathetic nervous system, including the three anatomical configurations and how they contribute to the overall sympathetic response.
Question
Acetylcholine is one of the most common neurotransmitters in the peripheral nervous system. Identify the branches of the peripheral nervous system for which acetylcholine is the neurotransmitter and describe the receptors responsible for responding to acetylcholine. Include the mechanisms whereby these receptors transduce the response to acetylcholine.
Question
Test anxiety involves worry and dread about test performance and often interferes with normal learning and lowers test performance. 20- 30% of American students have experienced test anxiety. Some causes of test anxiety include fear of failure, waiting until the last minute to study, and/or those who have had trouble taking tests in the past. List at least five symptoms of test anxiety. Explain what autonomic division are the cause of the symptoms and its effect on target organs. Finally, what drug might be prescribed to alleviate the symptoms of text anxiety and explain its mode of action?
Question
According to the concept of dual innervation, in most cases, the two branches of the autonomic nervous system innervate the same effector organs, but tend to have opposite effects on those organs.
Question
The primary hormone released from the adrenal medulla is norepinephrine.
Question
The sympathetic nervous system is sometimes called the thoracolumbar division of the autonomic nervous system.
Question
The parasympathetic nervous system exerts more discrete effects on effector organs than the sympathetic nervous system due to the independence of parasympathetic ganglia.
Question
Alpha adrenergic receptors have a greater affinity for norepinephrine than for epinephrine.
Question
Neurons that release norepinephrine are referred to as adrenergic.
Question
A motor unit consists of a skeletal muscle fiber (cell)and all of the motor neurons that innervate that skeletal muscle fiber.
Question
The preganglionic neurons of the sympathetic nervous system originate in the spinal cord from a region of gray matter called the intermediolateral cell column.
Question
The responses triggered by the binding of acetylcholine can be either excitatory or inhibitory, depending on the target cell in question.
Question
Acetylcholine binding to nicotinic cholinergic receptors always excites the postsynaptic cell.
Question
The nature of a response from the parasympathetic nervous system is determined by the anatomy of this system. Describe the anatomy of the parasympathetic nervous system and how that differs from the sympathetic nervous system.
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Deck 11: The Nervous System: Autonomic and Motor Systems
1
Which of the following descriptions of collateral ganglia is TRUE?

A)Collateral ganglia are part of the somatosensory system, located off of the afferent neuron just prior to entering the spinal cord dorsal horn.
B)Collateral ganglia are part of the somatic nervous system, located where the motor neuron leaves the ventral horn.
C)Collateral ganglia are located within a chain just outside the spinal cord and are the sites of communication between sympathetic preganglionic neurons and postganglionic neurons.
D)Collateral ganglia are in the sympathetic nervous system but distinct from the sympathetic chain, and they function as a site of communication between sympathetic preganglionic neurons and postganglionic neurons.
E)Collateral ganglia are located within the effector organs and are the sites of communication between parasympathetic preganglionic neurons and postganglionic neurons.
D
2
Which of the following contributes to the ability of the sympathetic nervous system to produce widespread responses within the body?

A)Several preganglionic neurons activate a single postganglionic neuron.
B)Multiple preganglionic neurons innervate each ganglion, sending out individual postganglionic neurons.
C)One preganglionic neuron can activate only one postganglionic neuron.
D)One preganglionic neuron sends collaterals to multiple ganglia, affecting multiple postganglionic neurons.
E)One postganglionic neuron branches into many collaterals that affect multiple organs.
D
3
Which of the following is located between the invaginations of the motor end plate of a neuromuscular junction?

A)nicotinic receptors
B)fi2 receptors
C)fi3 receptors
D)acetylcholinesterase
E)muscarinic receptors
D
4
What are swellings of postganglionic autonomic axons from which neurotransmitters are released called?

A)sympathetic trunks
B)ganglia
C)neuromuscular junctions
D)varicosities
E)parasympathetic chains
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5
Which of the following statements is TRUE of communication across the neuromuscular junction?

A)Synaptic communication to the muscle cell can be excitatory or inhibitory.
B)The end- plate potential is always of sufficient magnitude to depolarize the muscle cell to threshold to initiate an action potential.
C)Acetylcholine released from a motor neuron binds to muscarinic cholinergic receptors.
D)Acetylcholinesterase located in mitochondria of the motor neuron degrades acetylcholine to acetate and choline.
E)Acetylcholinesterase located in the cytosol of the motor neuron degrades acetylcholine to acetate and choline.
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6
What is the correct order for the steps of synaptic transmission at the motor end plate? 1. Acetylcholine binds to postsynaptic receptors.
2) Acetylcholine is released by exocytosis.
3) A graded depolarization is produced.
4) An action potential is produced on the muscle cell membrane.
5) Channels that primarily allow diffusion of sodium are opened.
6) Voltage- dependent calcium channels on the plasma membrane open.
7) An action potential arrives at the axon terminal.

A)7, 6, 2, 1, 5, 3, 4
B)7, 6, 2, 1, 3, 4, 6
C)7, 5, 2, 1, 3, 4, 6
D)6, 7, 2, 1, 3, 5, 4
E)5, 7, 6, 2, 1, 4, 3
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7
The presence of within varicosities initiates the release of neurotransmitter.

A)mechanically- gated Ca2+ channels
B)voltage- gated Ca2+ channels
C)mechanically- gated Na+ channels
D)voltage- gated Na+ channels
E)voltage- gated K+ channels
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8
Binding of norepinephrine or epinephrine to a(n)receptor will activate an inhibitory G protein which decreases the activity of adenylate cyclase and therefore cAMP synthesis while the binding of these two neurotransmitters to a receptor will do the exact opposite.

A)fi2 : fi1
B)a2 : a1
C)a1 : a2
D)fi1 : fi2
E)a2 : fi1
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9
Where do the preganglionic neurons of the sympathetic nervous system emerge from the spinal cord?

A)sacral region only
B)thoracic region only
C)lumbar and sacral regions
D)thoracic and lumbar regions
E)lumbar region only
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10
What enzyme degrades the neurotransmitter released from varicosities of parasympathetic postganglionic neurons?

A)choline acetyl transferase
B)catechol- O- methyltransferase only
C)monoamine oxidase only
D)catechol- O- methyltransferase and monoamine oxidase
E)acetylcholinesterase
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11
The change in membrane potential that occurs in skeletal muscle cells in response to acetylcholine binding to its receptors is called a(n)

A)repolarizing potential.
B)refractory period.
C)inhibitory post synaptic potential.
D)end- plate potential.
E)hyperpolarizing potential.
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12
Propranolol is a non- selective fi adrenergic receptor antagonist. It would be appropriate for a doctor to prescribe propranolol to treat

A)low blood pressure.
B)peptic ulcers.
C)myasthenia gravis.
D)hypertension.
E)asthma.
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13
At rest, what is the relative contribution of the sympathetic and parasympathetic nervous systems to the regulation of homeostasis?

A)Only the sympathetic system is active.
B)Only the parasympathetic system is active.
C)Both systems are active but the parasympathetic predominates.
D)Both systems are active but the sympathetic predominates.
E)Neither system is active.
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14
The somatic nervous system regulates the activity of

A)skeletal muscle.
B)many organs.
C)the cardiovascular system.
D)endocrine organs.
E)the kidneys.
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15
Actions at which class of adrenergic receptor generally have inhibitory effects?

A)a1
B)fi1
C)nicotinic
D)a1 and fi1
E)fi2
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16
With respect to their innervation, individual skeletal muscle fibers (cells)are innervated by

A)a single motor neuron.
B)multiple motor neurons.
C)a single motor neuron and autonomic neuron.
D)multiple motor neurons and autonomic neurons.
E)a single motor neuron and multiple autonomic neurons.
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17
The cranial nerve that innervates most of the viscera in the thoracic and abdominal cavities is the

A)IX, or glossopharyngeal nerve.
B)VII, or facial nerve.
C)X, or vagus nerve.
D)III, or oculomotor nerve.
E)VIII, or vestibulocochlear nerve.
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18
One of the adaptations that occur to muscles due to exercise is that contractions become stronger and steadier over time even with no change in muscle mass. Which statement below best explains why muscle contractions may become stronger?

A)The skeletal muscle contraction is enhanced by an increased input from the sympathetic nervous system.
B)Motor neurons are activated more rapidly to generate a stronger muscle contraction.
C)The action potentials sent by the motor neurons get larger and last longer to produce more force in the muscles.
D)More motor neurons are made so that more action potentials can be sent down to the muscles.
E)Muscle fibers reflexively start generating force even before the motor neurons send action potentials.
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19
What area of the brain initiates the fight- or- flight response by producing widespread activation of the sympathetic nervous system?

A)limbic system
B)hypothalamus
C)cerebellum
D)brainstem
E)amygdala
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20
What is the neurotransmitter released from motor neurons?

A)dopamine
B)acetylcholine
C)GABA
D)epinephrine
E)norepinephrine
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21
Parasympathetic preganglionic neurons release the neurotransmitter ; sympathetic preganglionic neurons release the neurotransmitter _ .

A)acetylcholine : norepinephrine
B)epinephrine : norepinephrine
C)norepinephrine : norepinephrine
D)norepinephrine : acetylcholine
E)acetylcholine : acetylcholine
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22
Which of the following best describes the general arrangement of the efferent limb of the autonomic nervous system?

A)one neuron
B)two neurons in parallel
C)two neurons in series
D)three neurons in series
E)three neurons in parallel
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23
Myasthenia gravis primarily affects women and its defining characteristic is fatigue of unusually rapid onset and severity following the use of certain muscle groups. What symptoms below best allude to the set of muscles affected by this disease?

A)difficulty moving the joints of the fingers and toes
B)relaxed bladder causing frequent urination
C)difficulty speaking, difficulty swallowing, and drooping eyelids
D)difficulty walking due to fatigue in the major muscles of the legs
E)difficulty in fine motor control of the fingers, especially the thumb
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24
The opening of a cation channel that allows both Na+ and K+ to move through will cause the membrane to _ _ because of the _.

A)depolarize : greater K+ electrochemical gradient as compared with Na+
B)hyperpolarize : greater K+ electrochemical gradient as compared with Na+
C)depolarize : greater Na+ electrochemical gradient as compared with K+
D)not change : same electrochemical gradient for K+ and Na+
E)hyperpolarize : greater Na+ electrochemical gradient as compared with K+
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25
Students who suffer from test anxiety often have some of the following symptoms: the need for frequent urination, dilated pupils, and a dry mouth. What branch of the autonomic nervous system would cause these symptoms?

A)enteric
B)somatic
C)voluntary
D)sympathetic
E)parasympathetic
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26
What is the primary mode of action of curare?

A)It causes the degradation of the enzyme acetylcholinesterase.
B)It decreases the amount of acetylcholine released from the synaptic terminal.
C)It decreases the number of functional receptors on the muscle cell by the process of phagocytosis, which impairs the ability of neurons to respond to acetylcholine.
D)It blocks communication at the neuromuscular junction by preventing acetylcholine from binding to nicotinic cholinergic receptors.
E)It blocks the sodium channels in the axon of the presynaptic axon.
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27
Which statement best describes the results of the autoimmune disease myasthenia gravis?

A)Communication at the neuromuscular junction is blocked by preventing acetylcholine from binding to nicotinic cholinergic receptors.
B)There is a decrease in the amount of acetylcholine released from the synaptic terminal.
C)A decrease in the number of functional receptors on the muscle cell surface impairs its ability to respond to acetylcholine.
D)There is degradation of the enzyme acetylcholinesterase.
E)There is blocking of sodium channels in the axon of the presynaptic axon.
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28
Located entirely within the autonomic ganglia, cells that modulate the flow of information to the target organ are called neurons.

A)ganglionic
B)intrinsic
C)intraganglionic
D)preganglionic
E)postganglionic
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29
Where are most of the autonomic nervous system control centers located?

A)brainstem
B)frontal lobe
C)limbic system
D)thalamus
E)spinal cord
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30
Scopolamine is a muscarinic antagonist that acts by blocking muscarinic acetylcholine receptors. Although it is not clear how scopolamine prevents nausea and vomiting due to motion sickness, which statement below best describes the mechanism of action for this drug?

A)Scopolamine works by preventing calcium influx at the axon terminal, therefore preventing the release of neurotransmitter.
B)Scopolamine works on the optic nerve blocking sodium channels so that the sight of motion does not make an individual sick.
C)Scopolamine causes chloride channels to open causing a subthreshold graded potential in the soma of the cell and, therefore, no action potential is ever generated that may cause motion sickness.
D)Scopolamine prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine.
E)Scopolamine breaks down acetylcholine in the synaptic cleft, therefore blocking the drug from entering the neuron.
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31
The autonomic nervous system innervates all the following effector organs and tissues EXCEPT

A)skeletal muscles.
B)adipose tissues.
C)endocrine glands.
D)cardiac muscles.
E)exocrine glands.
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32
Parasympathetic preganglionic neurons travel in what nerves?

A)pelvic nerves only
B)spinal nerves only
C)cranial nerves only
D)cranial and spinal nerves
E)cranial and pelvic nerves
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33
In what class of autonomic neuron and within what organelle is the enzyme monoamine oxidase located?

A)smooth ER of parasympathetic postganglionic neurons
B)mitochondria of sympathetic postganglionic neurons
C)lysosomes of sympathetic preganglionic neurons
D)synaptic vesicles of sympathetic postganglionic neurons
E)Golgi apparatus of parasympathetic postganglionic neurons
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34
Adrenergic receptors with the greatest affinity for epinephrine are receptors.

A)alpha 2
B)beta 1
C)beta 3
D)beta 2
E)alpha 1
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35
Preganglionic and postganglionic sympathetic neurons are anatomically arranged in what three patterns?

A)sympathetic, parasympathetic, and involuntary nervous systems
B)sympathetic chains, those that innervate the adrenal medulla, and collateral ganglia
C)nicotinic ganglia, adrenergic ganglia, and cholinergic ganglia
D)alpha, gamma, and beta cells
E)visceral, systemic, and cardiovascular
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36
Which of the following is indicative of the relative release of catecholamines from the adrenal medulla?

A)80% epinephrine : 20% norepinephrine
B)100% acetylcholine
C)80% norepinephrine : 20% dopamine
D)80% norepinephrine : 20% epinephrine
E)80% epinephrine : 20% dopamine
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37
fi2 adrenergic receptor agonists are used to treat acute asthma symptoms by eliciting a response similar to , which has a greater affinity for fi2 receptors and leads to dilation of the respiratory pathways.

A)atropine
B)epinephrine
C)cyclic AMP
D)norepinephrine
E)acetylcholine
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38
Sympathetic ganglia that are linked together and run in parallel on either side of the spinal column are called

A)collateral ganglia.
B)gray ramus.
C)sympathetic chains or trunks.
D)lateral horns.
E)white ramus.
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39
People who have done a lot of endurance training can have a resting heart rate of 50 beats per minute compared to the normal resting heart rate of 70- 80 beats per minute. This decreased heart rate in trained individuals is the partly result of

A)endorphins released from the brain which have an inhibitory effect on heart rate.
B)parasympathetic activity becoming more active and sympathetic activity becoming less active at rest.
C)sympathetic activity becoming more active and parasympathetic activity becoming less active at rest.
D)decreases in both sympathetic and parasympathetic activity.
E)increases in both sympathetic and parasympathetic activity.
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40
Which of the following physiological responses is associated with an elevation in parasympathetic nervous system activity?

A)shifting blood flow away from the gastrointestinal tract
B)increased contractile force of the heart
C)enhanced absorption of nutrients
D)enhanced mobilization of energy stores
E)increased heart rate
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41
Parasympathetic postganglionic neurons release the neurotransmitter ; sympathetic postganglionic neurons release the neurotransmitter .

A)norepinephrine : norepinephrine
B)acetylcholine : norepinephrine
C)epinephrine : norepinephrine
D)norepinephrine : acetylcholine
E)acetylcholine : acetylcholine
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42
What is the graded change in membrane potential that occurs at the motor end plate of skeletal muscle called?

A)inhibitory postsynaptic potential
B)muscarinic potential
C)end- plate potential
D)adrenergic potential
E)action potential
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43
Which of the following physiological responses is associated with elevated sympathetic nervous system activity?

A)increased contractile force of the heart
B)inhibition of cardiovascular function
C)enhanced digestion
D)decreased heart rate
E)enhanced absorption of nutrients
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44
The most abundant neurotransmitter in the peripheral nervous system is acetylcholine.
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45
How does latroxin, the venom of the black widow spider, cause muscle spasms and rigidity?

A)It stimulates acetylcholine release from motor neurons.
B)It inhibits acetylcholine release from motor neurons.
C)It stimulates acetylcholine release from autonomic preganglionic neurons.
D)It blocks nicotinic cholinergic receptors.
E)It inhibits the degradation of acetylcholine at all synapses.
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46
Postganglionic neurons of the autonomic nervous system release neurotransmitter from

A)neuromuscular junction.
B)axon hillock.
C)varicosities.
D)somas.
E)dendrites.
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47
The autonomic nervous system consists of efferent pathways with two peripheral neurons that travel in series from the central nervous system to the effector organ.
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48
Atropine, first derived from the Atropa belladonna plant, is a nicotinic receptor antagonist.
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49
Dual innervation of organs by the autonomic nervous system refers to the observation that

A)autonomic and somatic neurons innervate all organs.
B)both sympathetic and parasympathetic neurons innervate most organs.
C)autonomic neurons that innervate each target organ originate from two ganglia.
D)autonomic innervation involves preganglionic and postganglionic neurons.
E)two postganglionic sympathetic neurons innervate each target organ.
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50
Binding of acetylcholine to receptors will activate a G protein.

A)adrenergic
B)nicotinic
C)muscarinic
D)somatostatic
E)cholinergic
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51
Sympathetic preganglionic neurons exit the spinal cord via the _ root, and then join the spinal nerve. They leave the spinal nerve and enter the ganglion via the _ ramus. Most of the postganglionic fibers return to the spinal nerve via the _ ramus.

A)ventral : gray : white
B)dorsal : white : gray
C)dorsal : gray : white
D)ventral : white : gray
E)dorsal : gray: gray
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52
Which of the following endocrine glands is innervated by sympathetic preganglionic neurons?

A)pancreas
B)thyroid gland
C)anterior pituitary
D)adrenal cortex
E)adrenal medulla
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53
When the body is stressed, what is the relative contribution of the sympathetic and parasympathetic nervous systems to the regulation of homeostasis?

A)Only the parasympathetic system is active.
B)Only the sympathetic system is active.
C)Both systems are active but the parasympathetic predominates.
D)Both systems are active but the sympathetic predominates.
E)Neither system is active.
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54
Parasympathetic neurons from which cranial nerve innervate most of the viscera in the thoracic and abdominal cavities?

A)I
B)III
C)VII
D)IX
E)X
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55
Where in the central nervous system do the preganglionic neurons of the parasympathetic nervous system originate?

A)thoracic region of the spinal cord only
B)thoracic and lumbar regions of the spinal cord
C)brainstem and sacral region of the spinal cord
D)sacral region of the spinal cord only
E)lumbar region of the spinal cord only
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56
The somatic nervous system is often referred to as the system.

A)craniosacral
B)unconscious
C)voluntary
D)neuromuscular
E)involuntary
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57
Binding of acetylcholine to receptors causes by opening channels that primarily permit sodium to permeate the membrane.

A)nicotinic : a depolarization
B)nicotinic : no change in membrane potential
C)muscarinic : a hyperpolarization
D)muscarinic : a depolarization
E)nicotinic : a hyperpolarization
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58
Where on skeletal muscle is the highest density of nicotinic receptors?

A)motor end plate
B)dendrites
C)axon hillock
D)terminal bouton
E)motor unit
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59
The somatic nervous system provides both excitatory and inhibitory signals to skeletal muscle.
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60
Compared to norepinephrine, epinephrine has a greater affinity for what type of receptor?

A)muscarinic
B)nicotinic
C)fi2
D)fi1
E)a1
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61
For skeletal muscle to relax, the neural stimulation must decrease.
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62
Physiological stressors will cause parasympathetic nervous system activity to increase.
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63
The autonomic nervous system is also known as the involuntary nervous system.
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64
Describe the synaptic junctions between the neurons of the autonomic and somatic nervous systems and their effector organs.
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65
Norepinephrine is one of the more important neurotransmitters of the peripheral nervous system. Identify the branches of the peripheral nervous system for which norepinephrine is the neurotransmitter and describe the receptors responsible for responding to norepinephrine. Include the mechanisms whereby these receptors transduce the response to norepinephrine.
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66
The nature of a response from the sympathetic nervous system is determined by the anatomy of this system. Describe the general structure of the sympathetic nervous system, including the three anatomical configurations and how they contribute to the overall sympathetic response.
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67
Acetylcholine is one of the most common neurotransmitters in the peripheral nervous system. Identify the branches of the peripheral nervous system for which acetylcholine is the neurotransmitter and describe the receptors responsible for responding to acetylcholine. Include the mechanisms whereby these receptors transduce the response to acetylcholine.
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68
Test anxiety involves worry and dread about test performance and often interferes with normal learning and lowers test performance. 20- 30% of American students have experienced test anxiety. Some causes of test anxiety include fear of failure, waiting until the last minute to study, and/or those who have had trouble taking tests in the past. List at least five symptoms of test anxiety. Explain what autonomic division are the cause of the symptoms and its effect on target organs. Finally, what drug might be prescribed to alleviate the symptoms of text anxiety and explain its mode of action?
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69
According to the concept of dual innervation, in most cases, the two branches of the autonomic nervous system innervate the same effector organs, but tend to have opposite effects on those organs.
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70
The primary hormone released from the adrenal medulla is norepinephrine.
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71
The sympathetic nervous system is sometimes called the thoracolumbar division of the autonomic nervous system.
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72
The parasympathetic nervous system exerts more discrete effects on effector organs than the sympathetic nervous system due to the independence of parasympathetic ganglia.
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73
Alpha adrenergic receptors have a greater affinity for norepinephrine than for epinephrine.
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74
Neurons that release norepinephrine are referred to as adrenergic.
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75
A motor unit consists of a skeletal muscle fiber (cell)and all of the motor neurons that innervate that skeletal muscle fiber.
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76
The preganglionic neurons of the sympathetic nervous system originate in the spinal cord from a region of gray matter called the intermediolateral cell column.
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77
The responses triggered by the binding of acetylcholine can be either excitatory or inhibitory, depending on the target cell in question.
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78
Acetylcholine binding to nicotinic cholinergic receptors always excites the postsynaptic cell.
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79
The nature of a response from the parasympathetic nervous system is determined by the anatomy of this system. Describe the anatomy of the parasympathetic nervous system and how that differs from the sympathetic nervous system.
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