Deck 49: Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation
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Deck 49: Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation
1
pH is defined as
A) log [H +]
B) Ln [H +]
C) - log [H +]
D) -ln [H +]
E) -log ç
A) log [H +]
B) Ln [H +]
C) - log [H +]
D) -ln [H +]
E) -log ç
C
2
The fun ction o f che m ical bu ffers is to
A) Restore pH to normal following departures
B) Increase the effect of adding acid or base on blood pH
C) Bind up acid if acid is in excess or release acid if base is in excess
D) Equilibrate acids across cell mem branes
E) Excrete acid or base via the lungs
A) Restore pH to normal following departures
B) Increase the effect of adding acid or base on blood pH
C) Bind up acid if acid is in excess or release acid if base is in excess
D) Equilibrate acids across cell mem branes
E) Excrete acid or base via the lungs
C
3
Buffers abs orb the greatest am ount of H + ions per unit concentration of buffer when
A) The pH is much less than the pK
B) The pH is much greater than the pK
C) The pH is near the pK
D) pH is low
E) pH is high
A) The pH is much less than the pK
B) The pH is much greater than the pK
C) The pH is near the pK
D) pH is low
E) pH is high
C
4
If pH = 7, the n [H +] is
A) 1 mM
B) 1 µM
C) 7 mM
D) 7 µM
E) 0.1 µ M
A) 1 mM
B) 1 µM
C) 7 mM
D) 7 µM
E) 0.1 µ M
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5
Hyperventilation causes
A) An Increase in PaCO2 and an Increase in blood pH
B) An Increase in PaCO2 and a decrease in blood pH
C) A decrease in PaCO2 and an Increase in blood pH
D) A decrease in PaCO2 and a decrease in blood pH
E) Emphysema
A) An Increase in PaCO2 and an Increase in blood pH
B) An Increase in PaCO2 and a decrease in blood pH
C) A decrease in PaCO2 and an Increase in blood pH
D) A decrease in PaCO2 and a decrease in blood pH
E) Emphysema
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6
In the diagram provided, what point represents respiratory acidosis?
A) A
B) B
C) C
D) D
E) E
A) A
B) B
C) C
D) D
E) E
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7
In the Henderson-Hasselbalch equat ion, the units of [HCO -] are
A) M
B) mM
C) mm Hg
D) Atm
E) Pa
A) M
B) mM
C) mm Hg
D) Atm
E) Pa
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8
R es pir ato ry alk alo sis
A) Is caused by any condition that intereferes with lung gas exchange
B) Lowers plasma pH
C) Is a condition in which PaCO2 is reduced from norm al
D) Usually results from hyperventilation
E) Can be caused by exercise
A) Is caused by any condition that intereferes with lung gas exchange
B) Lowers plasma pH
C) Is a condition in which PaCO2 is reduced from norm al
D) Usually results from hyperventilation
E) Can be caused by exercise
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9
Hypoventilation causes
A) An Increase in PaCO2 and an Increase in blood pH
B) An Increase in PaCO2 and a decrease in blood pH
C) A decrease in PaCO2 and an Increase in blood pH
D) A decrease in PaCO2 and a decrease in blood pH
E) Emphysema
A) An Increase in PaCO2 and an Increase in blood pH
B) An Increase in PaCO2 and a decrease in blood pH
C) A decrease in PaCO2 and an Increase in blood pH
D) A decrease in PaCO2 and a decrease in blood pH
E) Emphysema
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10
R es pir ato ry ac ido sis
A) Is caused by hyperventilation
B) Low ers plasm a [H +] -
C) Does not cause changes in [HCO 3 ]
D) Lowers plasma [HCO 3 ]
E) Is caused by any condition that interferes with gas exchange in the lungs
A) Is caused by hyperventilation
B) Low ers plasm a [H +] -
C) Does not cause changes in [HCO 3 ]
D) Lowers plasma [HCO 3 ]
E) Is caused by any condition that interferes with gas exchange in the lungs
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11
In the diagram provided, what point represents uncompensated metabolic acidosis?
A) A
B) B
C) C
D) E'
E) E
A) A
B) B
C) C
D) E'
E) E
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12
In the Henderson-Hasselbalch equation, [HA] = [A-] when
A) The buffer capacity is maxim al
B) pH = pK
C) Acid [HA] is half neutralized with base
D) The slope of the titration curve (pH vs amount of strong base added) is minimal
E) All of the above
A) The buffer capacity is maxim al
B) pH = pK
C) Acid [HA] is half neutralized with base
D) The slope of the titration curve (pH vs amount of strong base added) is minimal
E) All of the above
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