Deck 48: Oxygen and Carbon Dioxide Transport

Question 1

The per cent of the net de livery of CO from tissue to lungs that is carried by HCO - is abo ut

A) 0 %
B) 5%
C) 10%
D) 40%
E) 85%

Answer 1

E

Question 2

Shifting the hemoglobin oxygen dissociation curve to the right

A) Is the same as reducing the affinity of hemoglobin for oxygen
B) Means that less oxygen is bound at a given PO₂
C) Makes it easier to unload oxygen in the tissues
D) M ea ns tha t he m og lob in b ind s o xyg en les s tig htly
E) All of the above

Answer 2

E

Question 3

Oxygen consum ption occurs

A) At the cell mem brane
B) Mainly in the endoplasmic reticulum
C) Mainly in the liver
D) M ain ly in th e b ra in
E) M ainly in th e m itoc ho nd ria

Answer 3

E

Question 4

Positive cooperativity mak es the oxygen disso ciation curve

A) Bip ha sic
B) Sigmoid-shaped
C) Pa ra bo lic
D) H ype rb olic
E) Linear

Question 5

The normal saturation of hemoglobin in arterial blood is

A) 100%
B) 95%
C) 75%
D) 46%
E) 40%

Question 6

O xyg en bin din g to he m og lob in

A) occurs with a stoichiometry of 4 O 2 molecules per Fe-containing heme group
B) sho ws neg ative c oop erativity
C) Is s im ilar in for m to its bin din g to m yog lob in b ind ing ex ce pt it b ind s tig hte r to he m og lob in
D) is gen erally sa turate d at P aO₂ of 40 mm Hg
E) none of the above

Question 7

In the figure, which curve represents the normal hemoglobin oxygen dissociation curve?

A) A
B) B
C) C
D) D
E) E

Question 8

Am ong the fo llowing , the hig hes t PCO₂ is fo un d in

A) T he air
B) M ois t tra ch ea l air
C) Alv eo lar air
D) Arterial Blood
E) Tissues

Question 9

Chloride transport as the driving force

A) Moves into RBCs in the tissues and out of RBCs in the lungs
B) Moves into RBCs in the tissues and in the lungs
C) Moves out of RBCs in the tissues and into the RBCs in the lungs
D) Moves out of RBCs in the tissues and in the lungs
E) Moves across the RBC m embrane but unrelated to its position in the circulation
20) The solubility of O₂ in water is about 0.003 mL dL

Question 10

Am ong the fo llowing , the hig hes t PO₂ is fo un d in

A) Air
B) M ois t tra ch ea l air
C) Alv eo lar air
D) Arterial Blood
E) Tissues

Question 11

Increasing the CO₂ in the tissues causes

A) a shift in the Hb (hem oglobin) saturation curve to the left
B) an upw ard shift in the Hb saturation curve
C) Hb to bind O 2 less strong ly
D) An Increased pH
E) none of the ab ove

Question 12

Which of the followin g D OE S N OT shift the hem oglo bin ox ygen diss ocia tion cu rve to the righ t?

A) Increased temp erature
B) Increased PO₂
C) Decreased pH
D) Increased PCO₂
E) Increased 2,3-diphosphoglycerate (2,3 DPG)

Question 13

Positive cooperativity means

A) Bind ing at on e site Increases the affinity of binding at a secon d vac ant site
B) Binding at a site on the protein is independent of occupancy of other sites.
C) Protein molecules bind together to allow oxygen binding
D) Protein-protein interaction is necessary for oxygen binding
E) The slop e of th e diss ocia tion cu rve is m axim al at low est P aO₂

Question 14

M yog lob in in m us cle ce lls

A) Stores oxygen
B) Binds Ca₂+
C) He lps c arry o xyg en to th e m itoc ho nd ria
D) H elp s r ela x m us cle
E) Both A and C are true