Deck 17: Polypharmacy

Question 1

One of the things affecting drug distribution is the bioavailability of the drug.Which of the following factors may affect the amount of a drug that reaches the systemic circulation? Select
All that apply.
1)Handling of the drug.
2)Dosage of the drug.
3)Solubility of the drug.
4)Route of administration.
5)Generic drug.

Answer 1

3, 4

Question 2

Which of the following is most affected by pharmacokinetic change?
1)Distribution of drugs.
2)Elimination of drugs.
3)Absorption of drugs.
4)Metabolism of drugs.

Answer 2

2

Question 3

Which of the following factors affect drug absorption? Select all that apply.
1)Metabolic diseases
2)Esophageal erosion
3)Kidney diseases
4)Drug-food interactions
5)Huntington's disease

Answer 3

1, 2, 4

Question 4

Biotransformation means chemical alteration of things such as nutrients, amino acids, toxins, and drugs in the body.In which organ does biotransformation occurs?
1)Intestines
2)Liver
3)Pancreas
4)Bile

Question 5

A patient is started on a low dose of a drug for safety but is never advanced to a therapeutic dose while another drug is added.Which of the following does this describe?
1)Preferences of care.
2)Risk-benefit ratio of drug.
3)Narrow therapeutic index of drug.
4)Clinical inertia.

Question 6

Which of the following is true regarding STOPP/START criteria for prescribing medications? Select all that apply.
1)Lists potential alternative drugs that can safely be used in older adults.
2)Valuable tool for prescribers, but they are not meant to be mandates for prescribing.
3)Screening tool to alert doctors to correct treatment.
4)Screening tool of older persons' potentially inappropriate prescriptions.
5)It is the Beers criteria that mandates prescribing.

Question 7

The aging process may alter the dynamic processes that drugs undergo to produce therapeutic effects.Which of the following are terms that refer to these changes? Select all that apply.
1)Pharmacodynamics
2)Prophylaxis
3)Pharmacology
4)Pharmacokinetics
5)Pharmacist

Question 8

Initial and ongoing assessment should be the protocol when prescribing medications. Designating and training office staff to do the initial medication review can save time but still
Requires review by the provider.Which of the following terms refers to a patient bringing in all
Current medications for review?
1)Brown bag
2)OTC
3)Rational polypharmacy
4)Magic bag

Question 9

It is important to know the pharmacodynamic influences of the drug.Which of the following statements are true regarding pharmacodynamics? Select all that apply.
1)A drug's pharmacodynamics describes the effect at the site of action.
2)Pharmacodynamics is concerned with the movement of drugs within the body.
3)A drug's pharmacodynamics describes the time and intensity of the drug effect.
4)Pharmacodynamics describes the rate and pathways by which drugs are eliminated from the body by metabolism and excretion.
5)Pharmacodynamics' fundamental concept is drug clearance.

Question 10

Which of the following is related to the incidence of gastric acidity declining with age because of decreased intestinal blood flow?
1)Drug metabolism
2)Drug distribution
3)Drug absorption
4)Drug elimination

Question 11

A patient sees the nurse practitioner for a post-hospitalization follow-up and presents new complaints with change in functional status.Which of the following should the nurse practitioner do? Select all that apply.
1)Evaluate for ADR.
2)Prescribe patient medications for the new symptoms.
3)Consult current resources for precautions before prescribing.
4)Prescribe antibiotics for the patient.
5)Leave as status quo.

Question 12

There are over 35 assessment tools currently available to assist providers with the prescribing of medications.Which of the following consists of a list of potentially inappropriate medications (PIMs)to be avoided in older adults?
1)STOPP
2)START
3)Beers criteria
4)ADRs

Question 13

Polypharmacy is a primary predictor for any undesired or unwanted consequences that can occur because of taking medications.Which is of the following is the correct term for these undesired or unwanted consequences?
1)Adverse drug reaction (ADR)
2)Prototype drug
3)Adverse drug event
4)Schedule II drugs

Question 14

After consultation with the patient, which of the following is prevented by prescribing only necessary drugs?
1)Pharmacodynamics
2)Polypharmacy
3)Pharmacokinetics
4)Pharmacy

Question 15

Drug distribution in the body is affected by aging and higher body fat.Which of the following is true regarding drugs distributed in fat? Select all that apply.
1)There is a wider effect in drugs distributed in fat.
2)The effect of drugs is less when distributed in fat.
3)There is prolonged action in drugs distributed in fat.
4)There is a more intense effect of drugs distributed in fat.
5)There is a shorter effect of drugs distributed in fat.