Deck 24: Reproductive System Drugs

Question 1

Women with a uterus should not use estrogen-alone therapy because it puts them at risk for which of the following a. Blood clots
B) Uterine cancer
C) Stroke
D) Osteoporosis

Answer 1

Estrogen is a female sex hormone produced by the ovary. Estrogen therapy is used for relieving the symptoms of menopause.
There is no risk of blood clots, stroke and osteoporosis associated with estrogen therapy in women with intact uterus.
Hence, the options (a), (c), and (d) are incorrect.
Estrogen therapy is associated with an increase in the risk of getting endometrial carcinoma in women having intact uterus.
Hence, the correct answer is option (b) uterine cancer.

Question 2

Estrogen therapy (i.e., estrogen alone) has been associated with an increased risk of endometrial cancer. Estrogen combined with which agent reduces this risk a. Testosterone
B) Androgens
C) Progestin
D) Progesterone agonist

Answer 2

Estrogen is a female sex hormone produced by the ovary. Estrogen therapy is used for relieving the symptoms of menopause.
Estrogen therapy is associated with an increase in the risk of getting endometrial carcinoma in women having intact uterus. Estrogen is not mixed with testosterone, androgens and progesterone agonist to prevent the risk of cancer.
Hence, the options (a), (b) and (d) are incorrect.
The risk of uterine cancer associated with estrogen alone therapy can be reduced by combining estrogen with progestin.
Hence, the correct answer is option (c) Progestin.

Question 3

A contraceptive preparation containing two sequences of progestin doses and less than 50 mcg of estrogen is called: a. Monophasic
B) Biph asic
C) Triphasic
D) Four-phasic

Answer 3

Monophasic preparations of contraceptives contain equal proportion of estrogen and progestin.
Hence, the option (a) is incorrect.
Triphasic preparations of contraceptives contain three sequences of progestin and less than 50 mcg of estrogen.
Hence, the option (c) is incorrect.
Four-phasic preparations contain four sequences of estradiol valerate and two sequences of progestin dienogest.
Hence, the option (d) is incorrect.
Biphasic contraceptives consist of two sequences of progestin and less than 50 mcg estrogen.
Hence, the correct answer is option (b) Biphasic.

Question 4

Dinoprostone intravaginal gel or vaginal insert is indicated for: a. Premature labor
B) Therapeutic abortion
C) Induction of labor
D) Cervical ripening

Question 5

Allison Cavanaugh is a 24-year-old female who has been experiencing painful and heavy-flow menses. At a recent visit to her gynecologist, she was diagnosed with endometriosis. The physician writes a prescription for an oral contraceptive containing estrogen and progestin and explains that this might help Allison's condition by:

A) Increasing the frequency of ovulation
B) Increasing the amount or thickness of cervical mucus
C) Decreasing the amount of pituitary hormones released
D) Creating a thin, atrophic endometrium not conducive to sustaining a fertilized ovum

Question 6

Oxytocin should be avoided for patients with a history of: a. Miscarriage
B) Diabetes mellitus
C) Endometriosis
D) Placenta previa

Question 7

Katrina Oosterlund is in her 31st week of pregnancy and has developed hypertension, 3+ edema in her ankles, and proteinuria. The OB physician is concerned that she may develop new-onset grand mal seizures related to eclampsia. She is admitted to the hospital and started on IV magnesium sulfate. Katrina is reluctant to start on the IV because she is concerned about the drug magnesium sulfate. The physician explains that the medication is necessary for her condition and will produce an anticonvulsant effect by:

A) Peripheral vasoconstriction
B) An increase in circulatory volume
C) Depressing the CNS and thereby causing cerebral vasodilation
D) The induction of bradycardia and a subsequent reduction in blood pressure

Question 8

A side effect of methylergonovine, given for the treatment of postpartum hemorrhage, can include: a. Fever
B) Nausea and vomiting
C) Urinary retention
D) Peripheral vasodilation

Question 9

Match the medications in the first column with the conditions they are used to treat. Conditions may be used more than once.
MedicationCondition
_____ Premarin a. Endometriosis
_____ Megace b. Menopausal symptoms
_____ Depo-Testosterone c. Prostate cancer
_____ Danocrine d. Erectile dysfunction
_____ Covaryx e. Hypogonadism
_____ terbutaline f. Uterine inertia in labor
_____ Cialis g. Infertility
_____ Levitra h. Preterm labor
_____ Pitocin i. Cachexia of AIDS

Question 10

A drug used primarily for pulmonary disorders but that can also be used for the management of preterm labor is: a. Oxytocin
B) Carboprost
C) Terbutaline
D) Misoprostol

Question 11

Katrina Oosterlund is in her 31st week of pregnancy and has developed hypertension, 3+ edema in her ankles, and proteinuria. The OB physician is concerned that she may develop new-onset grand mal seizures related to eclampsia. She is admitted to the hospital and started on IV magnesium sulfate. The nurse notes a physician order for an antidote in case of an overdose of magnesium sulfate. The drug she will have on hand in case of an overdose is:

A) Calcium carbonate
B) Glucagon
C) Calcium gluconate
D) Carboprost

Question 12

Maternal side effects of terbutaline include: a. Hyperglycemia
B) Hypoglycemia
C) Hyperthryoidism
D) Hyperkalemia

Question 13

Allison Cavanaugh is a 24-year-old female who has been experiencing painful and heavy-flow menses. At a recent visit to her gynecologist, she was diagnosed with endometriosis. Prior to writing the prescription for the contraceptive, the physician reviews Allison's medical history. This is important because contraceptives are contraindicated in patients with a history of:

A) Asthma
B) Thrombophlebitis
C) Peanut allergy
D) Breast augmentation

Question 14

Fetal side effects of terbutaline include: a. Hypercalcemia
B) Hypobilirubinemia
C) Tachycardia
D) Intra-abdominal bleeding

Question 15

Katrina Oosterlund is in her 31st week of pregnancy and has developed hypertension, 3+ edema in her ankles, and proteinuria. The OB physician is concerned that she may develop new-onset grand mal seizures related to eclampsia. She is admitted to the hospital and started on IV magnesium sulfate. Extreme caution should be exercised when administering magnesium sulfate due to its potential effects on the neonate. This includes the potential for:

A) Hypotension
B) Increased risk of seizure
C) Respiratory depression
D) Hypertension

Question 16

Extreme caution is required with the administration of oxytocin, along with constant fetal and maternal monitoring, to prevent which side effect a. Cervical stricture
B) Maternal desaturation
C) Maternal seizures
D) Uterine rupture

Question 17

Allison Cavanaugh is a 24-year-old female who has been experiencing painful and heavy-flow menses. At a recent visit to her gynecologist, she was diagnosed with endometriosis. The nurse instructs Allison on how to take the contraceptive. Which of the following instructions is most likely to be included in her teaching plan

A) Use a backup contraceptive for three months.
B) Take the oral contraceptive at the same time each day.
C) Note that oral contraceptives protect against HIV.
D) Take a drug holiday after taking the contraceptive for six months.

Question 18

Katrina Oosterlund is in her 31st week of pregnancy and has developed hypertension, 3+ edema in her ankles, and proteinuria. The OB physician is concerned that she may develop new-onset grand mal seizures related to eclampsia. She is admitted to the hospital and started on IV magnesium sulfate. What is one of the serious side effects of magnesium sulfate

A) Hypertension
B) Flaccid paralysis
C) Status asthmaticus
D) Severe dehydration

Question 19

Allison Cavanaugh is a 24-year-old female who has been experiencing painful and heavy-flow menses. At a recent visit to her gynecologist, she was diagnosed with endometriosis. What symptom would be most important for Allison to report to her physician after starting the oral contraceptive

A) Chest pain
B) Urinary frequency
C) Breast tenderness
D) Rash on chest

Question 20

Katrina Oosterlund is in her 31st week of pregnancy and has developed hypertension, 3+ edema in her ankles, and proteinuria. The OB physician is concerned that she may develop new-onset grand mal seizures related to eclampsia. She is admitted to the hospital and started on IV magnesium sulfate. While Katrina is receiving IV magnesium sulfate, she will be monitored closely for:

A) Vital signs and reflexes
B) Blood glucose levels
C) Hematocrit and hemoglobin
D) Creatinine clearance

Question 21

What possible side effect should a patient taking tadalafil report to a physician a. Insomnia
B) Vision abnormalities
C) Constipation
D) Tingling in the feet

Question 22

Which category of drugs has serious interactions with PDE inhibitors a. Nitrates
B) Anti-inflammatories
C) Muscle relaxants
D) Hypoglycemic agents