Question 1

Which medication classifications are associated with increasing the risk of developing acute generalized exanthematous pustulosis (AGEP) (Select all that apply.)&#10;A) Cephalosporins&#10;B) Calcium channel blockers&#10;C) Aminopenicillins&#10;D) Tuberculostatic agents&#10;E) Non-steroidal anti-inflammatory drugs (NSAIDS)

Accepted Answer

B, C, E

Question 2

A patient is taking a sulfonamide antibiotic and develops a rash that begins peeling. Which type of rash is suspected?&#10;A) Erythema multiforme&#10;B) Stevens-Johnson&#10;C) Urticaria&#10;D) Wheal and flare

Accepted Answer

Peeling of the skin is a characteristic feature of Stevens-Johnson syndrome, a serious and potentially life-threatening skin reaction often caused by sulfonamide antibiotics. Erythema multiforme may also cause a rash, but it typically does not involve skin peeling. Urticaria is characterized by raised, itchy welts on the skin, and wheal and flare is a type of skin reaction seen in allergy testing.

Deck 45: Cutaneous Adverse Drug Reactions