Deck 3: The Human Genome: Gene Structure and Function
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Deck 3: The Human Genome: Gene Structure and Function
1
Translation involves which type of RNA?
A) Messenger RNA (mRNA)
B) Ribosomal RNA (rRNA)
C) Transfer RNA (tRNA)
D) All of the above
E) None of the above
A) Messenger RNA (mRNA)
B) Ribosomal RNA (rRNA)
C) Transfer RNA (tRNA)
D) All of the above
E) None of the above
All of the above
2
Translation is always initiated at a codon for which amino acid?
A) Alanine
B) Glycine
C) Tryptophan
D) Methionine
E) Phenylalanine
A) Alanine
B) Glycine
C) Tryptophan
D) Methionine
E) Phenylalanine
Methionine
3
In humans, which of the following are mechanisms by which a single gene can produce multiple gene products?
A) Suppressor codons
B) Alternative stop codons
C) RNA splicing
D) Recombination
E) Use of tumor-associated transplantation antigen (TATA) boxes
A) Suppressor codons
B) Alternative stop codons
C) RNA splicing
D) Recombination
E) Use of tumor-associated transplantation antigen (TATA) boxes
RNA splicing
4
What types of sequences are located in the 5' region of human genes?
A) Exons and introns
B) Start and stop codons
C) Promoters and enhancers
D) Splice signals
E) Polyadenylation sequences
A) Exons and introns
B) Start and stop codons
C) Promoters and enhancers
D) Splice signals
E) Polyadenylation sequences
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5
This modification of cytosine phosphate guanine (CpG) islands is associated with transcriptional repression:
A) Phosphorylation
B) Protein binding
C) Methylation
D) Lipidation
E) None of the above
A) Phosphorylation
B) Protein binding
C) Methylation
D) Lipidation
E) None of the above
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6
DNA sequences that resemble known genes but are nonfunctional are called:
A) Pseudogenes
B) False genes
C) Dead genes
D) Faux genes
E) Noncoding genes
A) Pseudogenes
B) False genes
C) Dead genes
D) Faux genes
E) Noncoding genes
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7
Which of the following steps must a primary RNA transcript undergo before it becomes a fully processed, mature mRNA?
A) Capping, polyadenylation, and splicing
B) Splicing
C) Splicing and reverse transcription
D) Capping and splicing
E) Splicing and transport
A) Capping, polyadenylation, and splicing
B) Splicing
C) Splicing and reverse transcription
D) Capping and splicing
E) Splicing and transport
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8
What is the central dogma of molecular biology?
A) DNA to RNA to protein
B) Transcription to splicing to translation
C) Meiosis, recombination, fertilization
D) Mitosis, cell division, cell death
E) DNA synthesis, homologous pairing, recombination
A) DNA to RNA to protein
B) Transcription to splicing to translation
C) Meiosis, recombination, fertilization
D) Mitosis, cell division, cell death
E) DNA synthesis, homologous pairing, recombination
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9
Which of the following sequences is located in the 3' region of human genes?
A) Splice signals
B) Promoters
C) Start codons
D) Locus control regions
E) Polyadenylation sequences
A) Splice signals
B) Promoters
C) Start codons
D) Locus control regions
E) Polyadenylation sequences
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10
Which of the following describes the system of codons in our DNA?
A) Each codon encodes a unique amino acid
B) It is degenerate
C) Each codon specifies an amino acid
D) Codons are overlapping
E) The molecular link between codons and amino acids is mRNA
A) Each codon encodes a unique amino acid
B) It is degenerate
C) Each codon specifies an amino acid
D) Codons are overlapping
E) The molecular link between codons and amino acids is mRNA
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11
Which of the following are final products of a gene?
A) Protein
B) RNA
C) Exons
D) Both A and B
E) A, B, and C
A) Protein
B) RNA
C) Exons
D) Both A and B
E) A, B, and C
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12
Gene families can arise by which of the following mechanisms?
A) Transcription
B) Recombination
C) Gene duplication
D) Gene replication
E) All of the above
A) Transcription
B) Recombination
C) Gene duplication
D) Gene replication
E) All of the above
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