Deck 25: Water, Electrolyte, and Acid-Base Balance
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Deck 25: Water, Electrolyte, and Acid-Base Balance
1
Hyperventilation is most likely to cause
A) a blood pH higher than 7.45.
B) diuresis.
C) edema.
D) acidosis.
A) a blood pH higher than 7.45.
B) diuresis.
C) edema.
D) acidosis.
A
2
Which of the following is most likely to occur when output is less than intake?
A) Dehydration
B) Edema
C) Hypovolemia
D) Polyuria
A) Dehydration
B) Edema
C) Hypovolemia
D) Polyuria
Edema
3
Most body water is located within which space?
A) Interstitial
B) Intravascular
C) Intracellular
D) Transcellular
A) Interstitial
B) Intravascular
C) Intracellular
D) Transcellular
Intracellular
4
Water and chloride usually follow the movement of which cation?
A) Bicarbonate
B) Sodium
C) Potassium
D) Albumin
A) Bicarbonate
B) Sodium
C) Potassium
D) Albumin
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5
Kaliuresis refers to the urinary loss of
A) water.
B) albumin.
C) potassium.
D) sodium.
A) water.
B) albumin.
C) potassium.
D) sodium.
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6
Which of the following forms the greatest extracellular fluid compartment?
A) Lymph
B) Interstitial
C) Plasma
D) Transcellular
A) Lymph
B) Interstitial
C) Plasma
D) Transcellular
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7
Which of the following is true about interstitial fluid,plasma,lymph,and transcellular fluid?
A) Contain no electrolytes
B) Protein-free fluids
C) Classified as extracellular
D) pH less than 6 (highly acidic)
A) Contain no electrolytes
B) Protein-free fluids
C) Classified as extracellular
D) pH less than 6 (highly acidic)
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8
Excess diuresis is most likely to cause
A) edema.
B) overhydration.
C) blood volume depletion.
D) acidosis.
A) edema.
B) overhydration.
C) blood volume depletion.
D) acidosis.
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9
Which of the following is descriptive of normal saline?
A) Distilled water
B) 0.9% sodium chloride
C) Highly acidic
D) Contains albumin
A) Distilled water
B) 0.9% sodium chloride
C) Highly acidic
D) Contains albumin
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10
Poor skin turgor is most indicative of
A) cystitis.
B) acidosis.
C) edema.
D) dehydration.
A) cystitis.
B) acidosis.
C) edema.
D) dehydration.
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11
Which of the following is not a function of the lungs?
A) Oxygenation of blood
B) Excretion of carbon dioxide
C) Secretion of aldosterone and the regulation of Na+
D) Regulation of blood pH
A) Oxygenation of blood
B) Excretion of carbon dioxide
C) Secretion of aldosterone and the regulation of Na+
D) Regulation of blood pH
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12
Which of the following is not true of extracellular fluid?
A) Most body water is extracellular.
B) Plasma is extracellular fluid.
C) Transcellular fluid is extracellular.
D) There is more interstitial fluid than intravascular fluid.
A) Most body water is extracellular.
B) Plasma is extracellular fluid.
C) Transcellular fluid is extracellular.
D) There is more interstitial fluid than intravascular fluid.
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13
Which of the following is most likely to occur when output exceeds intake?
A) Diuresis
B) Polyuria
C) Hematuria
D) Dehydration
A) Diuresis
B) Polyuria
C) Hematuria
D) Dehydration
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14
Which of the following can be defined as an H⁺ donor?
A) Ion
B) Tincture
C) Acid
D) Bicarbonate
A) Ion
B) Tincture
C) Acid
D) Bicarbonate
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15
Hypoventilation is most likely to cause
A) acidosis.
B) edema.
C) renal excretion of bicarbonate.
D) hypokalemia.
A) acidosis.
B) edema.
C) renal excretion of bicarbonate.
D) hypokalemia.
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16
K⁺
A) is a cation.
B) is an acid.
C) neutralizes H+.
D) is the chief extracellular cation.
A) is a cation.
B) is an acid.
C) neutralizes H+.
D) is the chief extracellular cation.
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17
Bicarbonate (HCO₃-)is considered an anion because it
A) contains hydrogen.
B) contains carbon.
C) contains oxygen.
D) carries a negative charge.
A) contains hydrogen.
B) contains carbon.
C) contains oxygen.
D) carries a negative charge.
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18
Which of the following acts as a base?
A) H+
B) OH-
C) Calcium ion
D) Gastric juice
A) H+
B) OH-
C) Calcium ion
D) Gastric juice
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19
Metabolic acidosis,such as diabetic ketoacidosis,is most likely to cause
A) hypoventilation.
B) Kussmaul respirations.
C) the renal excretion of bicarbonate.
D) the renal retention of H+.
A) hypoventilation.
B) Kussmaul respirations.
C) the renal excretion of bicarbonate.
D) the renal retention of H+.
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20
Which fluid compartment is located between the cells and is also called tissue fluid?
A) Lymph
B) Plasma
C) Interstitial
D) Transcellular
A) Lymph
B) Plasma
C) Interstitial
D) Transcellular
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21
Hyperkalemia refers to an increase in the blood levels of which ion?
A) Hydrogen
B) Bicarbonate
C) Calcium
D) Potassium
A) Hydrogen
B) Bicarbonate
C) Calcium
D) Potassium
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22
Which ion determines the resting membrane potential of nerve and muscle?
A) Sodium
B) Calcium
C) Hydrogen
D) Potassium
A) Sodium
B) Calcium
C) Hydrogen
D) Potassium
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23
Most diuretics increase urine production by blocking the effects of which cation?
A) Calcium
B) Bicarbonate
C) Chloride
D) Sodium
A) Calcium
B) Bicarbonate
C) Chloride
D) Sodium
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24
Which of the following is most likely to develop in an anxious hyperventilating patient?
A) Respiratory acidosis
B) Alkalosis
C) A decrease in plasma pH
D) Ketoacidosis
A) Respiratory acidosis
B) Alkalosis
C) A decrease in plasma pH
D) Ketoacidosis
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25
Which hormone stimulates the kidneys to reabsorb calcium and to excrete phosphate?
A) ADH
B) Aldosterone
C) Parathyroid hormone
D) Erythropoietin
A) ADH
B) Aldosterone
C) Parathyroid hormone
D) Erythropoietin
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26
What does urinary specific gravity measure?
A) Plasma H+ concentration
B) Hydration status of the body
C) Plasma potassium
D) The buffering capacity of the blood
A) Plasma H+ concentration
B) Hydration status of the body
C) Plasma potassium
D) The buffering capacity of the blood
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27
Which of the following is characteristic of acidosis?
A) pH of 7.55
B) A decrease in the concentration of hydrogen ion in the blood
C) Urinary excretion of bicarbonate
D) pH less than 7.35
A) pH of 7.55
B) A decrease in the concentration of hydrogen ion in the blood
C) Urinary excretion of bicarbonate
D) pH less than 7.35
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28
A patient is admitted with severe emphysema and a PO₂ of 85.He also has a blood pH of 7.25 and a serum bicarbonate of 40 mEq/liter.Which of the following is the accurate description?
A) Metabolic acidosis and respiratory compensation
B) Metabolic alkalosis with a respiratory compensation
C) Respiratory alkalosis with a renal compensation
D) Respiratory acidosis with a renal compensation
A) Metabolic acidosis and respiratory compensation
B) Metabolic alkalosis with a respiratory compensation
C) Respiratory alkalosis with a renal compensation
D) Respiratory acidosis with a renal compensation
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29
Retention of which ion causes water retention and edema formation?
A) Potassium
B) Hydrogen
C) Sodium
D) Bicarbonate
A) Potassium
B) Hydrogen
C) Sodium
D) Bicarbonate
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30
Which of the following is a buffer pair?
A) PTH, aldosterone
B) ADH, ANF
C) HCO3-, H2CO3
D) Sodium, potassium
A) PTH, aldosterone
B) ADH, ANF
C) HCO3-, H2CO3
D) Sodium, potassium
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31
More than 99% of which cation is stored in the bones and teeth?
A) Potassium
B) Hydrogen
C) Chloride
D) Calcium
A) Potassium
B) Hydrogen
C) Chloride
D) Calcium
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32
Which ion determines pH?
A) Sodium
B) Hydrogen
C) Bicarbonate
D) Potassium
A) Sodium
B) Hydrogen
C) Bicarbonate
D) Potassium
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33
Which of the following is most likely to develop in a patient who hypoventilates because of a chronic respiratory disease,such as emphysema?
A) Kussmaul respirations
B) A decrease in the plasma concentration of hydrogen ion
C) An increase in plasma pH
D) Acidosis
A) Kussmaul respirations
B) A decrease in the plasma concentration of hydrogen ion
C) An increase in plasma pH
D) Acidosis
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34
Which group is incorrect?
A) Cations: sodium, potassium, calcium
B) Acid-base imbalances: acidosis, alkalosis
C) Lines of defense against acid-base imbalance: buffers, lungs, kidneys
D) Transcellular fluids: aqueous humor, cerebrospinal fluid, plasma
A) Cations: sodium, potassium, calcium
B) Acid-base imbalances: acidosis, alkalosis
C) Lines of defense against acid-base imbalance: buffers, lungs, kidneys
D) Transcellular fluids: aqueous humor, cerebrospinal fluid, plasma
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35
Which hormone causes the kidneys to retain sodium and to excrete potassium?
A) ADH
B) Erythropoietin
C) Aldosterone
D) PTH
A) ADH
B) Erythropoietin
C) Aldosterone
D) PTH
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36
Which condition is caused by vomiting stomach contents?
A) Hyperkalemia
B) Hypernatremia and blood volume expansion
C) Hypocalcemic tetany
D) Alkalosis
A) Hyperkalemia
B) Hypernatremia and blood volume expansion
C) Hypocalcemic tetany
D) Alkalosis
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37
Which of the following is the chief extracellular cation?
A) Chloride
B) Calcium
C) Sodium
D) Potassium
A) Chloride
B) Calcium
C) Sodium
D) Potassium
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38
Respiratory rate is most sensitive to the effects of which ion?
A) Na+
B) K+
C) H+
D) Cl-
A) Na+
B) K+
C) H+
D) Cl-
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39
Which of the following anions buffers H⁺?
A) Ca2+
B) HCO3-
C) Na+
D) K+
A) Ca2+
B) HCO3-
C) Na+
D) K+
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40
Which condition stimulates Kussmaul respirations?
A) Respiratory acidosis
B) Respiratory alkalosis
C) Ketoacidosis
D) Hypocalcemic tetany
A) Respiratory acidosis
B) Respiratory alkalosis
C) Ketoacidosis
D) Hypocalcemic tetany
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41
Which group is incorrect?
A) Anions: bicarbonate, chloride, phosphate
B) Lines of defense against acid-base imbalance: buffers, lungs, kidneys
C) Transcellular fluids: aqueous humor, cerebrospinal fluid, synovial fluid
D) Hormones: aldosterone, ADH, ANP, urea
A) Anions: bicarbonate, chloride, phosphate
B) Lines of defense against acid-base imbalance: buffers, lungs, kidneys
C) Transcellular fluids: aqueous humor, cerebrospinal fluid, synovial fluid
D) Hormones: aldosterone, ADH, ANP, urea
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42
An unconscious diabetic patient with a blood sugar of 450 mg/dL has an elevated temperature and is experiencing Kussmaul respirations.You suspect that
A) he is excreting large amounts of bicarbonate in his urine.
B) his PO2 is normal or high-normal.
C) his blood pH is 7.25.
D) Two of the above are true.
A) he is excreting large amounts of bicarbonate in his urine.
B) his PO2 is normal or high-normal.
C) his blood pH is 7.25.
D) Two of the above are true.
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43
Which of the following is least descriptive of dehydration?
A) Tenting
B) Anasarca
C) Hypovolemia
D) Concentrated plasma
A) Tenting
B) Anasarca
C) Hypovolemia
D) Concentrated plasma
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44
Which of the following best indicates the role of albumin in water balance?
A) Blocks the renal reabsorption of Na+
B) Enhances the renal excretion of K+
C) Maintains plasma oncotic pressure
D) "Plugs up" capillary pores, keeping water in the plasma
A) Blocks the renal reabsorption of Na+
B) Enhances the renal excretion of K+
C) Maintains plasma oncotic pressure
D) "Plugs up" capillary pores, keeping water in the plasma
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45
Which of the following is the trigger for the release of ADH?
A) Decreased blood volume
B) Renin
C) Dehydration
D) More than one of the above are true.
A) Decreased blood volume
B) Renin
C) Dehydration
D) More than one of the above are true.
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46
The determination of daily weights is used to monitor
A) serum K+.
B) diuretic therapy.
C) concentration of plasma protein.
D) pH.
A) serum K+.
B) diuretic therapy.
C) concentration of plasma protein.
D) pH.
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47
A change of pH from 7.40 to 7.25
A) is indicative of expanded blood volume.
B) is indicative of alkalosis.
C) reflects an increase in the amount of H+ in the blood.
D) is within normal limits.
A) is indicative of expanded blood volume.
B) is indicative of alkalosis.
C) reflects an increase in the amount of H+ in the blood.
D) is within normal limits.
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48
Which group is incorrect?
A) Ions: sodium, potassium, calcium, bicarbonate, chloride
B) Lines of defense against acid-base imbalance: buffers, lungs, kidneys
C) Extracellular fluid: intravascular, interstitial, transcellular
D) Substances that are normally found in a sample of urine: urea, creatinine, glucose
A) Ions: sodium, potassium, calcium, bicarbonate, chloride
B) Lines of defense against acid-base imbalance: buffers, lungs, kidneys
C) Extracellular fluid: intravascular, interstitial, transcellular
D) Substances that are normally found in a sample of urine: urea, creatinine, glucose
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49
Plasma oncotic pressure
A) is caused primarily by salt (sodium chloride).
B) "pulls" water into the capillaries from the interstitium.
C) pushes water out of the capillaries into the interstitium.
D) increases the flow of lymph.
A) is caused primarily by salt (sodium chloride).
B) "pulls" water into the capillaries from the interstitium.
C) pushes water out of the capillaries into the interstitium.
D) increases the flow of lymph.
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50
A patient with pulmonary edema is receiving furosemide (Lasix),a kaliuretic diuretic.He has lost 6.6 lb over a 48-hr period.Which statement is true?
A) His urinary output has decreased.
B) He has lost water weight.
C) He will become hyperkalemic if the furosemide is continued.
D) The loss of 6.6 lb causes "tenting."
A) His urinary output has decreased.
B) He has lost water weight.
C) He will become hyperkalemic if the furosemide is continued.
D) The loss of 6.6 lb causes "tenting."
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51
Hypocalcemia is most likely to
A) cause blood volume expansion (hypervolemia).
B) be treated with IV potassium.
C) cause tetany.
D) be caused by excess parathyroid hormone activity.
A) cause blood volume expansion (hypervolemia).
B) be treated with IV potassium.
C) cause tetany.
D) be caused by excess parathyroid hormone activity.
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52
A patient with pulmonary edema is receiving furosemide (Lasix),a kaliuretic diuretic.He has lost 6.6 lb over a 48-hr period.Which of the following statements is true?
A) He is probably hyperkalemic secondary to the diuretic therapy.
B) He has lost 12 L of water.
C) His skin is "tenting."
D) He has lost 3 L of water.
A) He is probably hyperkalemic secondary to the diuretic therapy.
B) He has lost 12 L of water.
C) His skin is "tenting."
D) He has lost 3 L of water.
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53
Which of the following is most likely to cause acidosis?
A) Persistent vomiting
B) Accumulation of plasma H+
C) Renal loss of albumin
D) Diuresis
A) Persistent vomiting
B) Accumulation of plasma H+
C) Renal loss of albumin
D) Diuresis
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54
Third spacing
A) is caused by aggressive diuretic therapy.
B) describes a severe state of hypovolemia and dehydration.
C) involves only the interstitial space.
D) can result in an abnormal accumulation of large amounts of water.
A) is caused by aggressive diuretic therapy.
B) describes a severe state of hypovolemia and dehydration.
C) involves only the interstitial space.
D) can result in an abnormal accumulation of large amounts of water.
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55
Aldosterone
A) is released in response to hypovolemia.
B) causes Na+ excretion.
C) causes K+ reabsorption.
D) determines the permeability of the collecting duct to water.
A) is released in response to hypovolemia.
B) causes Na+ excretion.
C) causes K+ reabsorption.
D) determines the permeability of the collecting duct to water.
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56
Which of the following is (are)true of Na⁺?
A) Is the chief extracellular anion
B) Helps regulate extracellular volume
C) Is regulated by ADH
D) All of the above
A) Is the chief extracellular anion
B) Helps regulate extracellular volume
C) Is regulated by ADH
D) All of the above
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57
A drug that decreases the synthesis of aldosterone
A) decreases blood pressure.
B) causes hypernatremia.
C) causes hypokalemia.
D) does all of the above.
A) decreases blood pressure.
B) causes hypernatremia.
C) causes hypokalemia.
D) does all of the above.
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58
Hyperkalemia
A) refers to an elevated serum calcium level.
B) generally develops in response to declining renal function.
C) is often caused by a kaliuretic diuretic.
D) is caused by excess aldosterone.
A) refers to an elevated serum calcium level.
B) generally develops in response to declining renal function.
C) is often caused by a kaliuretic diuretic.
D) is caused by excess aldosterone.
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59
Which of the following is an example of metabolic acidosis with a respiratory compensation?
A) Morphine overdose and diuresis
B) Persistent vomiting and hypoventilation
C) Ketoacidosis and Kussmaul respirations
D) Hypocalcemic tetany and hyperventilation
A) Morphine overdose and diuresis
B) Persistent vomiting and hypoventilation
C) Ketoacidosis and Kussmaul respirations
D) Hypocalcemic tetany and hyperventilation
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60
Which of the following is most likely to happen when fatty acids are broken down rapidly and incompletely?
A) The plasma pH decreases, causing metabolic alkalosis.
B) The patient hypoventilates in an attempt to correct the pH disturbance.
C) Ketoacids are produced, causing metabolic acidosis.
D) The plasma [H+] decreases.
A) The plasma pH decreases, causing metabolic alkalosis.
B) The patient hypoventilates in an attempt to correct the pH disturbance.
C) Ketoacids are produced, causing metabolic acidosis.
D) The plasma [H+] decreases.
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61
Which of the following conditions is most apt to decrease glomerular filtration rate (GFR)?
A) Overhydration
B) Hypotension
C) Administration of a diuretic for the treatment of edema
D) Water intoxication
A) Overhydration
B) Hypotension
C) Administration of a diuretic for the treatment of edema
D) Water intoxication
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62
Which of the following is true of hyperkalemia?
A) Also causes blood volume expansion and hypertension
B) Refers to an elevation in serum potassium
C) Is most often due to impaired respiratory function
D) Is due to an accumulation of urea in the blood
A) Also causes blood volume expansion and hypertension
B) Refers to an elevation in serum potassium
C) Is most often due to impaired respiratory function
D) Is due to an accumulation of urea in the blood
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63
Which of the following is most apt to cause a hypocalcemic tetany?
A) Hyperventilation
B) Rapid and excess fat catabolism
C) Metabolic acidosis
D) pH < 7.35
A) Hyperventilation
B) Rapid and excess fat catabolism
C) Metabolic acidosis
D) pH < 7.35
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64
An osmotic diuresis is most commonly caused by
A) ketonuria.
B) albuminuria.
C) glucosuria.
D) hypoglycemia.
A) ketonuria.
B) albuminuria.
C) glucosuria.
D) hypoglycemia.
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65
A deficiency of ADH,called diabetes insipidus,is characterized by
A) glucosuria and an osmotic diuresis.
B) polyuria and polydipsia.
C) Kussmaul respirations and hyperventilation.
D) edema formation and sodium retention.
A) glucosuria and an osmotic diuresis.
B) polyuria and polydipsia.
C) Kussmaul respirations and hyperventilation.
D) edema formation and sodium retention.
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66
A drug that blocks the renal reabsorption of sodium
A) decreases the renal excretion of Na+.
B) increases the amount of urine.
C) decreases the excretion of bicarbonate.
D) always increases the reabsorption of K+.
A) decreases the renal excretion of Na+.
B) increases the amount of urine.
C) decreases the excretion of bicarbonate.
D) always increases the reabsorption of K+.
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67
Excessive secretion of ADH,as occurs with head injury,is most likely to cause
A) tenting.
B) blood volume expansion.
C) diuresis.
D) hypernatremia.
A) tenting.
B) blood volume expansion.
C) diuresis.
D) hypernatremia.
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68
Which of the following is a pH descriptive of ketoacidosis?
A) 7.50
B) pH > 7.45
C) 14.0
D) 7.25
A) 7.50
B) pH > 7.45
C) 14.0
D) 7.25
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69
Under which condition will the renal reabsorption of bicarbonate increase?
A) As a compensatory mechanism for respiratory acidosis
B) Whenever blood pH exceeds 7.45
C) As a compensatory mechanism for metabolic alkalosis
D) Whenever a person hyperventilates
A) As a compensatory mechanism for respiratory acidosis
B) Whenever blood pH exceeds 7.45
C) As a compensatory mechanism for metabolic alkalosis
D) Whenever a person hyperventilates
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70
This anion is an important part of a major buffer pair and therefore plays an important role in acid-base regulation.
A) Na+
B) Bicarbonate
C) HCO3-
D) More than one of the above are true.
A) Na+
B) Bicarbonate
C) HCO3-
D) More than one of the above are true.
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71
A patient is ventilating at a rate of 8 to 10 respirations/min,having been heavily medicated for pain.Which of the following is true? The patient is (may)
A) develop a respiratory acidosis.
B) experiencing Kussmaul respirations.
C) experiencing diuresis.
D) likely to develop a metabolic alkalosis.
A) develop a respiratory acidosis.
B) experiencing Kussmaul respirations.
C) experiencing diuresis.
D) likely to develop a metabolic alkalosis.
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72
Where does most of the body's acid come from?
A) It is reabsorbed from the urine by the kidneys.
B) Metabolic reactions within the body
C) Ingestion of fruit juices
D) Ingestion of a variety of sources of bicarbonate
A) It is reabsorbed from the urine by the kidneys.
B) Metabolic reactions within the body
C) Ingestion of fruit juices
D) Ingestion of a variety of sources of bicarbonate
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73
Which of the following conditions is most apt to cause a dilutional hyponatremia?
A) Excess ingestion of water
B) Dehydration
C) Hypotension
D) Diaphoresis
A) Excess ingestion of water
B) Dehydration
C) Hypotension
D) Diaphoresis
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74
Generally speaking the movement of Na+ determines the
A) blood pH.
B) blood glucose.
C) secretion of PTH.
D) movement of water.
A) blood pH.
B) blood glucose.
C) secretion of PTH.
D) movement of water.
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75
Which of the following is true about these percentages: 60% and 28%? They represent the amount of
A) water eliminated as urine and through the skin and lungs.
B) Na+ and K+ reabsorbed by the kidneys in response to aldosterone.
C) water ingested through moist food and metabolism.
D) Na+ and K+ reabsorbed in response to ADH secretion.
A) water eliminated as urine and through the skin and lungs.
B) Na+ and K+ reabsorbed by the kidneys in response to aldosterone.
C) water ingested through moist food and metabolism.
D) Na+ and K+ reabsorbed in response to ADH secretion.
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76
Which of the following is true of dehydration?
A) Is characterized by poor skin turgor and "tenting"
B) Is accompanied by an decrease in urine specific gravity
C) Causes a shift of water from the vasculature into the interstitium
D) Is generally treated with a diuretic
A) Is characterized by poor skin turgor and "tenting"
B) Is accompanied by an decrease in urine specific gravity
C) Causes a shift of water from the vasculature into the interstitium
D) Is generally treated with a diuretic
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77
With carbon dioxide retention,CO? + H?O
A) H2O2.
B) H+ + HCO3-.
C) bicarbonate.
D) H2O + H2O.
A) H2O2.
B) H+ + HCO3-.
C) bicarbonate.
D) H2O + H2O.
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