Question 1

What is the most common histologic type of endometrial cancer?&#10;A) squamous cell carcinoma&#10;B) endometrioid adenocarcinoma&#10;C) clear cell carcinoma&#10;D) papillary serous carcinoma

Accepted Answer

Endometrioid adenocarcinoma is the most common histologic type of endometrial cancer, accounting for approximately 80% of cases.

Question 2

Incidence rates of endometrial cancer in the United States are highest in _____ women.&#10;A) African American&#10;B) Hispanic&#10;C) Asian/Pacific Islander&#10;D) non-Hispanic white

Accepted Answer

Non-Hispanic white women have the highest incidence rates of endometrial cancer in the United States compared to other racial and ethnic groups.

Question 3

What is the estimated median age at diagnosis of endometrial cancer?&#10;A) 45&#10;B) 54&#10;C) 62&#10;D) 74

Accepted Answer

The estimated median age at diagnosis of endometrial cancer is around 62 years.

Question 4

Which of the following is associated with a reduced risk for endometrial cancer?&#10;A) parity&#10;B) infertility&#10;C) earlier age at menarche&#10;D) spontaneous or induced abortion

Accepted Answer

Parity is associated with a reduced risk for endometrial cancer because pregnancy leads to periods of anovulation and progesterone exposure, which counteracts the effects of estrogen on the endometrium.

Question 5

Which of the following is associated with an increased risk for endometrial cancer?&#10;A) uterine fibroids&#10;B) daily aspirin regimen&#10;C) consuming more than two alcoholic drinks per day&#10;D) the use of an intrauterine device (IUD)

Accepted Answer

Consuming more than two alcoholic drinks per day is associated with an increased risk for endometrial cancer due to the potential effects of alcohol on hormone levels.

Question 6

The use of what medication has been linked to an increased risk of endometrial cancer?&#10;A) penicillin&#10;B) zolpidem&#10;C) raloxifene&#10;D) tamoxifen

Accepted Answer

Tamoxifen, a selective estrogen receptor modulator, has been associated with an increased risk of endometrial cancer due to its estrogen-like effects on the uterine lining.

Question 7

Obesity is one of the strongest and most well-established risk factors for endometrial cancer.

Accepted Answer

Obesity is a significant risk factor for endometrial cancer due to increased estrogen levels from excess adipose tissue, which can stimulate the endometrial lining.

Question 8

Endometrial cancer is primarily a disease of industrialized countries.

Accepted Answer

Endometrial cancer is more common in industrialized countries due to factors such as higher rates of obesity, lower fertility rates, and lifestyle factors that are more prevalent in these regions.

Question 9

The American Cancer Society recommends that all women undergo annual screening for endometrial cancer beginning at age 35.

Accepted Answer

The American Cancer Society does not recommend annual screening for endometrial cancer for all women starting at age 35. Screening is typically recommended for women with specific risk factors.

Question 10

Some research data seems to suggest that cigarette smoking may decrease the risk of endometrial cancer.

Accepted Answer

Some studies have indicated that smoking may lower estrogen levels, which could potentially reduce the risk of endometrial cancer, although smoking has many other harmful health effects.

Question 11

Hypertension is known to be an independent risk factor for endometrial cancer.

Accepted Answer

The answer of Hypertension is known to be an independent...

Question 12

List three reasons why African Americans with endometrial cancer are more likely than non-Hispanic white women to die from it.

Accepted Answer

The answer of List three reasons why African Americans with...

Question 13

What genetic defect is associated with increased risk of endometrial cancer?

Accepted Answer

The answer of What genetic defect is associated with increased...

Question 14

What is the unopposed estrogen hypothesis?

Accepted Answer

The answer of What is the unopposed estrogen hypothesis?...

Question 15

Why is the theory that night shift workers may have a higher risk of developing endometrial cancer plausible?

Accepted Answer

The answer of Why is the theory that night shift...

Deck 28: Endometrial Cancer