Deck 38: Epidemiology of Brain Tumors

Question 1

In 2018, brain/CNS tumors were diagnosed in 296,851 individuals and caused 241,037 deaths, about 2.3% of all cancer deaths.

Answer 1

True

Question 2

Since 1990, reported numbers of deaths from brain tumors and new cases have doubled in both men and women in the world population.

Answer 2

True

Question 3

Increases in the new cases of brain tumors in recent years are primarily the result of better detection using MRI and other imaging techniques.

Answer 3

True

Question 4

In the US population, brain cancer is the leading cause of cancer mortality in individuals under the age of 35 years.

Question 5

The age-specific frequency of newly diagnosed malignant brain tumors shows an initial peak during adolescence and a second peak in older adults.

Question 6

Approximately one third of brain tumors diagnosed in adults are malignant gliomas.

Question 7

Approximately one third of brain tumors diagnosed in adults are malignant meningiomas.

Question 8

Glioblastoma Multiforme is the most common and the most aggressive of all malignant gliomas.

Question 9

Exposure to high doses of radiation increases the risk of most forms of brain tumors.

Question 10

Intensive mobile cell phone use has been found to increase the risk of glioma development.

Question 11

The risk of developing a glioma is higher in men than women.

Question 12

The risk of developing a meningioma is higher in men than women.

Question 13

Estrogen replacement therapy increases the risk of developing meningioma in women.

Question 14

Individuals with allergies have an increased risk of developing glioma.

Question 15

More than 70% of childhood brain tumors are malignant gliomas.

Question 16

Approximately what percentage of brain tumors are diagnosed in children or adolescents?

A) 1-5%
B) 5-10%
C) 10-15%
D) 15-20%

Question 17

The most common type of childhood brain tumor is:

A) meningioma.
B) malignant glioma.
C) pituitary tumor.
D) neurofibroma.

Question 18

Gliomas and meningiomas account for approximately what percentage of brain tumors in adults?

A) 25%
B) 50%
C) 67%
D) 99%

Question 19

The risk factors for malignant glioma include all of the following except:

A) ionizing radiation.
B) genetic predisposition.
C) immunosuppressive drugs used in organ transplantation.
D) intensive mobile cell phone use.

Question 20

Meningioma in women occurs in excess in patients with what form of cancer?

A) Cervical cancer
B) Ovarian cancer
C) Breast cancer
D) Colon cancer

Question 21

A deletion of the short arm of either chromosome 1 or chromosome 9 is the "genetic signature" of:

A) glioblastoma multiforme.
B) astrocytoma.
C) oligodendroglioma.
D) retinoblastoma.

Question 22

Surgical menopause in young women occasionally precedes the development and diagnosis of what type of brain tumor?

A) Pituitary tumor
B) Retinoblastoma
C) Pineal tumor
D) Acoustic neuroma

Question 23

The jump in rates of brain tumors among children in the US during 1975-1985 has been attributed to which of the following concurrent developments?

A) Enhanced detected by MRI
B) Increased exposure to ionizing radiation
C) Widespread discontinuation of aspirin in children
D) a and c are correct
E) a, b, and c are all correct.

Question 24

Characterize the different types of brain tumors in children and adults.

Question 25

Discuss the global burden of brain tumors.

Question 26

Briefly discuss the profile of pediatric brain tumors.

Question 27

Briefly discuss the gender distribution of gliomas and the prognosis of patients diagnosed with this form of brain tumor.

Question 28

Discuss findings of studies of mobile phone use and the development of brain tumors.

Question 29

Discuss findings of studies of ionizing radiation and the development of brain tumors.

Question 30

Discuss the risk factors for meningioma.

Question 31

Describe genetic syndromes and cytogenetic abnormalities that predispose to brain tumor development.

Question 32

Discuss the abrupt jump in childhood brain tumor rates that occurred during 1975-1985.

Question 33

Discuss the possible role of immunosuppression in the development of brain tumors.

Question 34

Discuss the epidemiology of pituitary tumors.

Question 35

Discuss findings of studies of allergies and the development of brain tumors.