Deck 28: Epidemiology of Cancer of External Male Genitalia

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Question
In 2018, 34,475 men were diagnosed with cancer of the penis, and 15,138 deaths were attributed to this malignancy.
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Question
Carcinomas of the penis are rare among men living in developed countries but are relatively common among the male populations of some underdeveloped nations.
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Rates are very low among Israeli Jewish men (0.1 per 100,000) who are circumcised shortly after birth and among Muslim men (0.2 per 100,000) who are circumcised during childhood.
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In contrast, rates are much higher (3 to 10 per 100,000) among men living in certain parts of the world where circumcision is rare.
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The incidence of carcinoma of the penis increases steadily throughout life, and the rates are highest for elderly men, aged 70 years or older.
Question
Infection of the male genitalia by oncogenic strains of human papilloma virus has not been confirmed to play an etiologic role in a subset of cases of penile cancer.
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There is very little evidence suggesting that neonatal circumcision reduces the risk of carcinoma of the penis.
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Phimosis refers to circumferential fibrosis of preputial tissue (foreskin) in uncircumcised men that leads to narrowing and inability to retract the penile foreskin over the glans penis.
Question
Phimosis in uncircumcised men is a significant risk factor for the development of carcinoma of the penis.
Question
Recent reports suggest there may be synergism between HPV and HIV infection in elevating the risk of developing carcinoma of the penis.
Question
Percival Pott first reported the development of cancer of the scrotum in what occupational group?

A)Copper miners
B)Chimney sweeps
C)Coal miners
D)Brewers
Question
Which of the following terms does not refer to in situ carcinoma of the penis?

A) Lichen Sclerosus
B) Bowenoid papulosis
C) Bowen's disease
D) Erythroplasia of Queyrat
Question
What type of HPV infection is associated with the highest risk of developing carcinoma of the penis?

A) HPV6
B) HPV11
C) HPV16
D) HPV18
Question
Which of the following exposures is not a risk factor for cancer of the scrotum?

A) Agent Orange
B) Coal tar
C) Mineral oil
D) Arsenic
Question
Strategies for the prevention of carcinoma of the penis include all of the following except:

A) circumcision early in life.
B) limiting promiscuous sexual activity.
C) avoiding social drinking.
D) avoiding tobacco smoking.
Question
Discuss the global epidemiology of cancer of the penis.
Question
Briefly describe the role of circumcision in the prevention of cancer of the penis.
Question
Describe the risk factors for cancer of the penis.
Question
Discuss the association of phimosis and carcinoma of the penis.
Question
Discuss the role HPV and HIV in the development of carcinoma of the penis.
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Deck 28: Epidemiology of Cancer of External Male Genitalia
1
In 2018, 34,475 men were diagnosed with cancer of the penis, and 15,138 deaths were attributed to this malignancy.
True
2
Carcinomas of the penis are rare among men living in developed countries but are relatively common among the male populations of some underdeveloped nations.
True
3
Rates are very low among Israeli Jewish men (0.1 per 100,000) who are circumcised shortly after birth and among Muslim men (0.2 per 100,000) who are circumcised during childhood.
True
4
In contrast, rates are much higher (3 to 10 per 100,000) among men living in certain parts of the world where circumcision is rare.
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5
The incidence of carcinoma of the penis increases steadily throughout life, and the rates are highest for elderly men, aged 70 years or older.
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6
Infection of the male genitalia by oncogenic strains of human papilloma virus has not been confirmed to play an etiologic role in a subset of cases of penile cancer.
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7
There is very little evidence suggesting that neonatal circumcision reduces the risk of carcinoma of the penis.
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8
Phimosis refers to circumferential fibrosis of preputial tissue (foreskin) in uncircumcised men that leads to narrowing and inability to retract the penile foreskin over the glans penis.
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9
Phimosis in uncircumcised men is a significant risk factor for the development of carcinoma of the penis.
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10
Recent reports suggest there may be synergism between HPV and HIV infection in elevating the risk of developing carcinoma of the penis.
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11
Percival Pott first reported the development of cancer of the scrotum in what occupational group?

A)Copper miners
B)Chimney sweeps
C)Coal miners
D)Brewers
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12
Which of the following terms does not refer to in situ carcinoma of the penis?

A) Lichen Sclerosus
B) Bowenoid papulosis
C) Bowen's disease
D) Erythroplasia of Queyrat
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13
What type of HPV infection is associated with the highest risk of developing carcinoma of the penis?

A) HPV6
B) HPV11
C) HPV16
D) HPV18
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14
Which of the following exposures is not a risk factor for cancer of the scrotum?

A) Agent Orange
B) Coal tar
C) Mineral oil
D) Arsenic
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15
Strategies for the prevention of carcinoma of the penis include all of the following except:

A) circumcision early in life.
B) limiting promiscuous sexual activity.
C) avoiding social drinking.
D) avoiding tobacco smoking.
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16
Discuss the global epidemiology of cancer of the penis.
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17
Briefly describe the role of circumcision in the prevention of cancer of the penis.
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18
Describe the risk factors for cancer of the penis.
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19
Discuss the association of phimosis and carcinoma of the penis.
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20
Discuss the role HPV and HIV in the development of carcinoma of the penis.
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