Deck 9: Drug Therapy for Pulmonary Disorders

Question 1

Status asthmaticus ______________.

A)can be caused by too frequent applications of leukotriene antagonists
B)can be precipitated by the formation of airflow impairing mucus plugs
C)is usually self-limiting
D)All of the above

Answer 1

can be precipitated by the formation of airflow impairing mucus plugs

Question 2

Which of the following statements is false regarding beta 2 agonists used to treat asthma?

A)They stimulate bronchial beta 2 receptors.
B)They are divided into short- and long-acting drugs.
C)Used long term they can cause tolerance.
D)Given orally they are more effective than those used by inhalation.

Answer 2

Given orally they are more effective than those used by inhalation.

Question 3

Theophylline ______________.

A)is the generic name for caffeine
B)blocks muscarinic receptors causing bronchodilation
C)is often the oral drug of first choice
D)can cause a number of adverse drug interactions

Answer 3

can cause a number of adverse drug interactions

Question 4

Cromolyn and nedocromil ______________.

A)inhibit the release of histamine and leukotrienes from mast cells
B)cause bronchodilation by stimulating H1 receptors
C)can quickly terminate an asthmatic attack
D)are seldom used because of their adverse reactions

Question 5

Which of the following drugs are considered short-term relievers for asthma?

A)b₂ agonists
B)Oral steroids
C)Inhaled steroids
D)Leukotriene antagonists

Question 6

Alpha agonists used to treat rhinitis ______________.

A)dilate blood vessels and decrease vessel permeability
B)can cause a rebound effect
C)can cause orthostatic hypotension
D)are the only agents which have been shown to be effective in rhinitis

Question 7

Inflamed bronchi can become hyper-active in response to all of the following except ______________.

A)exercise
B)cold, dry air
C)allergens
D)All of the above

Question 8

Exercise induced asthma ______________.

A)is a relative rare occurrence
B)will get worse the more a person exercises
C)can be prevented by using a short-acting beta 2 agonist 15-60 minutes before exercise
D)has been shown not to be influenced by warm-up procedures before exercise

Question 9

You are exercising a teenage girl who has a history of asthma.During the course of her therapy session she begins to complain of cough,dyspnea,and wheezing.Unfortunately she has left her inhaler at home.Vital signs include RR,42 breaths/minutes; pulse rate,120 bpm; and blood pressure,150/70 mm Hg.What is the most immediate course of action?

A)Send her home.
B)Have her breathe into a bag.
C)Call her home to see if someone can bring in her inhaler.
D)Call 911.

Question 10

Which one of the following is the most appropriate drug to reverse her acute bronchoconstriction?

A)Inhaled α₂ agonists
B)Inhaled anticholinergics
C)Inhaled mast cell stabilizers
D)Oral steroids

Question 11

Which of the following drugs are used to lessen the symptoms of cystic fibrosis?

A)Mucolytic agents
B)β-Blockers
C)Calcium channel blockers
D)Agonists

Question 12

You are treating a 67-year-old male with a diagnosis of chronic obstructive pulmonary disease.In addition,he has a history of hypertension and congestive heart disease.Which of the following drugs would be contraindicated?

A)Diuretic
B)ACE inhibitor
C)ACE receptor blocker
D)Inhaled steroids

Question 13

Leukotriene affecting drugs ______________.

A)can be divided into synthesis inhibitors and receptor blockers
B)are only used as monotherapy
C)are contraindicated in children
D)are highly effective but carry many adverse reactions

Question 14

Chronic obstructive pulmonary disease is treated with all of the following drugs except ______________.

A)corticosteroids
B)beta 2 agonists
C)muscarinic antagonists
D)antihistamines

Question 15

Measured dose inhalation devices must be used properly.Which of the following is false?

A)They should be kept at room temperature and shaken before use.
B)They should be held about 2-4 inches from the mouth (unless a spacer is provided).
C)The patient should exhale before use.
D)The patient should activate the device while inhaling slowly for 2-5 seconds.

Question 16

Endogenous substances which cause bronchoconstriction include all of the following except
______________.

A)acetylcholine
B)histamine
C)epinephrine
D)leukotrienes

Question 17

Further questioning of this patient revealed that she suffers at least four asthmatic episodes per week.Which of the following drugs would be most useful in providing a sustained resolution of her symptoms?

A)IV steriods
B)Leukotriene antagonists
C)Inhaled α₂ agonists
D)Coffee