Deck 23: Drugs for Gastrointestinal Disorders

Question 1

Which of the following defines probiotics?

A)Microorganisms that stimulate the growth of beneficial organisms within the gastrointestinal
B)Bulking agents that reduce constipation predominant IBS
C)Antispasmodic agents that act directly on intestinal smooth muscle
D)Saline laxatives that increase osmotic pressure in the small intestine

Answer 1

Microorganisms that stimulate the growth of beneficial organisms within the gastrointestinal

Question 2

In what way does regular exercise benefit patients with Irritable Bowel Syndrome (IBS)with constipation?

A)Causes fluid release into the large intestine
B)Reduces oral intake
C)Improves gastric emptying
D)Promotes reabsorption of fatty acids

Answer 2

Improves gastric emptying

Question 3

A patient who is currently receiving warfarin following a Deep Venous Thrombosis (DVT)takes bismuth subsalicylate for recurrent diarrhea.What of the following red flags should the therapist watch for indicating an adverse drug reaction?

A)Orthostatic hypotension
B)Bruising
C)Tachycardia
D)Peripheral neuropathy

Answer 3

Bruising

Question 4

NSAIDs contribute to GI ulcer formation by which of the following mechanisms?

A)Vasoconstriction of the venous portal system
B)Enhanced release of mucus
C)Increased acid secretion
D)Inhibits COX-1 mediated prostaglandin production

Question 5

Patients taking histamine 2 blockers need to be monitored for adverse drug reactions due to which of the following reasons?

A)They inhibit the liver microsomal metabolizing enzymes.
B)They inhibit intestinal absorption of important minerals and nutrients.
C)They reduce basal food-stimulated gastric acid release.
D)They increase bicarbonate secretion.

Question 6

Which of the following explains the mechanism of action of antacids?

A)Reduces secretion of mucus
B)Stimulates somatostatin
C)Neutralizes the gastric acidity
D)Reduces prostaglandin release

Question 7

Helicobacter pylori infection may lead to peptic ulcer disease due to which of the following mechanisms?

A)A reduction in acid secretion
B)Induction of a host immune response to eliminate the organism
C)Production of an anticholinergic effect
D)Stimulation of pancreatic lipase

Question 8

What is the role of serotonergic agonists in the treatment of irritable bowel syndrome with constipation?

A)Block reabsorption of fluids from the intestine
B)Increase intestinal motility
C)Promote increased fluid intake
D)Relax intestinal smooth muscle

Question 9

Proton pump inhibitors are effective for the treatment of gastritis due to which of the following mechanism?

A)Inhibition of H⁺/k⁺-ATPase pump
B)Stimulation of the release prostaglandins
C)Reduction of input to the chemoreceptor trigger zone
D)Stimulation of mechanoreceptors in the muscular wall of the stomach

Question 10

Which of the following drug categories may be used as an anti-emetic?

A)Anticholinerigcs
B)Antihistamines
C)Neuroleptic agents
D)All of the above