Deck 1: Pharmaceutical Tablet Manufacturing

Question 1

Which one of these is responsible for hardness of tablet?

A)Die Filling
B)Compression force
C)Both (a) & (b)
D)None of these

Answer 1

Both (a) & (b)

Question 2

Friablilator is operated for _________ revolutions per minute.

A)100
B)75
C)50
D)25

Answer 2

100

Question 3

In dissolution test, flask is maintained at:

A)31° C ± 0.5C
B)41° C ± 0.1C
C)39° C ± 0.6C
D)40° C ± 0.1C

Answer 3

31° C ± 0.5C

Question 4

Enteric coated tablet disintegrate in ____ hrs in simulated intestinal fluid.

A)1
B)2
C)3
D)4

Question 5

Separation of tablet in 2 or more distinct layer is

A)Capping
B)Mottling
C)Lamination
D)Air entrapment

Question 6

Capping is prevented by using:

A)Flat
B)Circular
C)Square
D)Rectangular

Question 7

Plating of punch forces is done by:

A)Chromium
B)Zinc
C)Iron
D)Any of the above

Question 8

Unequal distribution of color is called

A)Capping
B)Lamination
C)Mottling
D)None of the above

Question 9

________ is directly compressible excipient

A)Spray Dried lactose
B)Dibasic calcium phosphate
C)None of the above
D)Any of the above

Question 10

Sta-Rx-1500 contain ______ % of moisture

A)15
B)10
C)18
D)50

Question 11

pH of small intestine is

A)1-2
B)3-4
C)6
D)7-8

Question 12

Perforated pan is used for

A)Sugar coating
B)Film coating
C)Both (a) & (b)
D)None of the above

Question 13

Subcoating is done to

A)Round the edges
B)Increase in the bulk of tablet
C)Both (a) & (b)
D)Make water resistant

Question 14

Which one is the example of Opacifier

A)TiO₂
B)MgO
C)Silicates
D)None of the above

Question 15

Empty capsule has moisture content in the range of

A)60%
B)12-15%
C)50-70%
D)30%

Question 16

Which machine is designed for filling of pellets?

A)Rotofil
B)Rotosort
C)Ordinary machine
D)None of these

Question 17

Soft gelatin capsule should not contain more than ____ ppm of iron as impurity?

A)5
B)15
C)40
D)60

Question 18

Enteric resin used for coating is?

A)Cellulose acetate Pthalate
B)Zein
C)Shellac
D)All of the above

Question 19

Base for chewable tablets include

A)Mannitol
B)Glucose
C)Lactose
D)None

Question 20

Enteric coated tablet disintegrate in

A)Stomach
B)Liver
C)Intestine
D)Mouth

Question 21

Not used as tablet glidant:

A)Colloidal Silica
B)Starch
C)Talc
D)Magnesium stearate

Question 22

Rotosort is used for

A)Sorting filled capsules
B)Filling the capsule
C)Mixing of powder
D)None of the above

Question 23

Hardness of tablet is measured by

A)Pfizer tester
B)Erweka Tester
C)Strong Cobb
D)All of the above

Question 24

Whiskering (a tablet defect) is observed with the use of _____ punch.

A)Convex
B)Flat
C)Concave
D)Biconvex