Deck 1: Liposomes

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Question
Liposomes are spherical structures, usually between in diameter……………..

A)80nm-100nm
B)60nm-100nm
C)55nm-1000nm
D)15nm-1000nm
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Question
Liposomes consists of a bilayer of…………………

A)Hydrophilic molecules
B)Hydrophobic molecules
C)Both a and b
D)None
Question
Liposomes have half-life …………….

A)Longer
B)Shorter
C)Intermediate
D)Both a and b
Question
Liposome phospholipids undergoes ………………

A)Oxidation
B)Hydrolysis
C)Acetylation
D)Both a and b
Question
Intermediate sized unilamellar vesicles are prepared by

A)Sonication
B)High pressure extrusion technique
C)Detergent dialysis
D)Both b and c
Question
The diameter of Small unilamellar vesicles is

A)20-100nm
B)20-1000nm
C)10-100nm
D)100nm-400nm
Question
Tranfersome belongs to the classification according to

A)Composition
B)Application
C)Function
D)None of the above
Question
Liposomes with ___________number of lamella are called as "pauci -lamellar liposomes".

A)Lower
B)Higher
C)Single
D)None of the above
Question
Passive Loading Technique includes…………..

A)Lyophilization
B)Proliposomes
C)Solvent dispersion
D)Both a and b
Question
Loading of the entrapped agents before/during the manufacture procedure is known as…………

A)Active loading
B)Passive loading
C)Both a and b
D)None of the above
Question
Drawback of Lipid hydration method is

A)Low internal volume
B)High encapsulation efficiency
C)Size distribution is homogenous
D)None of the above
Question
Tip of sonicator is directly engrossed into liposome dispersion in……………

A)Bath sonication
B)Probe sonication
C)None of the above
D)all
Question
The resulting liposomes from French pressure cell extrusion are ______than sonicated SUVs.

A)Smaller
B)Equal
C)Larger
D)all
Question
To produce a microemulsion of small vesicles at least _______ circulations are required

A)at least 20 circulation but not greater than 200
B)10 circulations
C)at least 200 circulation but not greater than 2000
D)at least 2 circulations but not greater than 10
Question
Dried reconstituted vesicles method is performed in…………..

A)Solvent dispersion
B)Mechanical dispersion
C)Both a and b
D)none
Question
Solvent vaporization is also known as………………….

A)Ether injection
B)Ethanol injection
C)Double emulsification
D)Reverse-phase evaporation
Question
Temperature used for Ether Injection method is______ or under reduced pressure.

A)15-25 ?C
B)55-65 ?C
C)55-85 ?C
D)None of the above
Question
Ketoconazole liposomes are given by…………….

A)Lungs
B)Oral
C)Transdermal
D)Intravenous
Question
Amphotericin B liposomes are given……………..

A)Lungs
B)Oral
C)Transdermal
D)Intravenous
Question
In niosomes phospholipids are ………………

A)Present
B)Absent
C)Both a or b
D)None
Question
Pharmacosome belongs to the classification according to

A)Composition
B)Function
C)Application
D)None of the above
Question
Which of the following can be incorporated into a liposome?

A)Only drugs and viruses
B)Only Peptides and viruses due to similar characteristics
C)Only viruses
D)Drugs, peptides, viruses, bacteria
Question
How are MLV liposomes made?

A)2-10 bilayers of lipid
B)Series of concentric bilayers of lipid
C)The single bilayer of lipid
D)100 bilayer of lipid
Question
How are OLV liposomes made?

A)2-10 bilayers of lipid
B)Series of concentric bilayers of lipid
C)A single bilayer of lipid
D)100 bilayer of lipid
Question
Which of the following is a characteristic of the parental controlled drug release system by liposomes?

A)Free flowing powders
B)Aqueous solutions
C)Lipid bilayer enclosing the drug
D)Administration of emulsions
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Deck 1: Liposomes
1
Liposomes are spherical structures, usually between in diameter……………..

A)80nm-100nm
B)60nm-100nm
C)55nm-1000nm
D)15nm-1000nm
15nm-1000nm
2
Liposomes consists of a bilayer of…………………

A)Hydrophilic molecules
B)Hydrophobic molecules
C)Both a and b
D)None
Both a and b
3
Liposomes have half-life …………….

A)Longer
B)Shorter
C)Intermediate
D)Both a and b
Shorter
4
Liposome phospholipids undergoes ………………

A)Oxidation
B)Hydrolysis
C)Acetylation
D)Both a and b
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5
Intermediate sized unilamellar vesicles are prepared by

A)Sonication
B)High pressure extrusion technique
C)Detergent dialysis
D)Both b and c
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6
The diameter of Small unilamellar vesicles is

A)20-100nm
B)20-1000nm
C)10-100nm
D)100nm-400nm
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7
Tranfersome belongs to the classification according to

A)Composition
B)Application
C)Function
D)None of the above
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8
Liposomes with ___________number of lamella are called as "pauci -lamellar liposomes".

A)Lower
B)Higher
C)Single
D)None of the above
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9
Passive Loading Technique includes…………..

A)Lyophilization
B)Proliposomes
C)Solvent dispersion
D)Both a and b
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10
Loading of the entrapped agents before/during the manufacture procedure is known as…………

A)Active loading
B)Passive loading
C)Both a and b
D)None of the above
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11
Drawback of Lipid hydration method is

A)Low internal volume
B)High encapsulation efficiency
C)Size distribution is homogenous
D)None of the above
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12
Tip of sonicator is directly engrossed into liposome dispersion in……………

A)Bath sonication
B)Probe sonication
C)None of the above
D)all
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13
The resulting liposomes from French pressure cell extrusion are ______than sonicated SUVs.

A)Smaller
B)Equal
C)Larger
D)all
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14
To produce a microemulsion of small vesicles at least _______ circulations are required

A)at least 20 circulation but not greater than 200
B)10 circulations
C)at least 200 circulation but not greater than 2000
D)at least 2 circulations but not greater than 10
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15
Dried reconstituted vesicles method is performed in…………..

A)Solvent dispersion
B)Mechanical dispersion
C)Both a and b
D)none
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16
Solvent vaporization is also known as………………….

A)Ether injection
B)Ethanol injection
C)Double emulsification
D)Reverse-phase evaporation
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17
Temperature used for Ether Injection method is______ or under reduced pressure.

A)15-25 ?C
B)55-65 ?C
C)55-85 ?C
D)None of the above
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18
Ketoconazole liposomes are given by…………….

A)Lungs
B)Oral
C)Transdermal
D)Intravenous
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19
Amphotericin B liposomes are given……………..

A)Lungs
B)Oral
C)Transdermal
D)Intravenous
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20
In niosomes phospholipids are ………………

A)Present
B)Absent
C)Both a or b
D)None
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21
Pharmacosome belongs to the classification according to

A)Composition
B)Function
C)Application
D)None of the above
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22
Which of the following can be incorporated into a liposome?

A)Only drugs and viruses
B)Only Peptides and viruses due to similar characteristics
C)Only viruses
D)Drugs, peptides, viruses, bacteria
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23
How are MLV liposomes made?

A)2-10 bilayers of lipid
B)Series of concentric bilayers of lipid
C)The single bilayer of lipid
D)100 bilayer of lipid
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24
How are OLV liposomes made?

A)2-10 bilayers of lipid
B)Series of concentric bilayers of lipid
C)A single bilayer of lipid
D)100 bilayer of lipid
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25
Which of the following is a characteristic of the parental controlled drug release system by liposomes?

A)Free flowing powders
B)Aqueous solutions
C)Lipid bilayer enclosing the drug
D)Administration of emulsions
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